[Date Prev][Date Next][Thread Prev][Thread Next][Date Index][Thread Index]
[SANET-MG] mon 863 report 3
Mon863 - Pusztai 3 report From GM Watch
This is the third of three reports to be found on the Internet.
Report on the newly provided data: “Kidney Weight Data from Two 90 Day
Rat Feeding Studies with Corn Hybrids that Contain Event MON 863” by
Monsanto Company, St Louis, Missouri USA; 20th October 2004..
This contract study has been done with two hybrids of MON 863 by the WIL
Research Laboratory in the USA in response to some of the criticisms
expressed by the French Commission du Genie Biomoleculaire
(CGB)concerning the significant differences in kidney weights found in
the original study between rats that had been fed diets containing MON
863 and its near isogenic non-GM corn line.
The report presents only some of the results of the feeding study
including kidney weights, final body weights and brain weights of rat
fed diets containing these two hybrid GM lines (+ the original
previously obtained results with MON 863 for comparison) and the near
isogenic line diet, respectively. The feeding study therefore cannot be
fully evaluated. However, as it can be assumed that it was done to a
similar design as the original study with the MON 863 GM corn, all
criticisms made to that study should equally apply to this new study.
Thus, the large range of individual values of the various parameters and
the consequently large SD values make it difficult to establish whether
there were any significant differences between the different groups.
Forexample, kidney weights of male rats varied between 2.58 to 3.48 g,
or 2.72 to 3.66 g, or 2.42 to 3.67 in some of the groups. Without being
able to pair and follow through the appropriate test- and control
animals and clearly assign individual values to individual animals whose
starting weight, feed intake, and other parameters were similar and
closely controlled throughout the experiment, no proper conclusion about
the outcome of the feeding study is possible. Moreover, similar large
differences were found in female rats and the differences in body
weights or brain weights of all rats were similarly large, this study,
therefore, has not advanced our understanding whether the genetic
modification of corn as this has been done in the case of MON 863 or in
these two GM hybrids carries any special risks for mammalian health.
As detailed in my previous main report on MON 863, this type of
relatively crude and insensitive study on organ weights should only be
regarded as starting point in GM food risk assessment. We need more
detailed structural, pathohistological, immunological, hormonal and
functional dynamic studies into organ function, right down to the
cellular and subcellular level to pinpoint whether feeding mammals with
GM food/feed represents any nutritional or physiological stress for the
organs and whether it may jeopardize the health of the animal. There are
many such methods in GM- or related fields it is, therefore, regrettable
that the Monsanto scientists have not made better use of them.
1st November 2004
Email this Article to a Friend
To unsubscribe from SANET-MG:
1- Visit http://lists.sare.org/archives/sanet-mg.html to unsubscribe or;
2- Send a message to <firstname.lastname@example.org> from the address subscribed to the list. Type "unsubscribe sanet-mg" in the body of the message.
Visit the SANET-MG archives at: http://lists.sare.org/archives/sanet-mg.html
For more information on grants and other resources available through the SARE program, please visit http://www.sare.org.