[Date Prev][Date Next][Thread Prev][Thread Next][Date Index][Thread Index]

Re: [SANET-MG] glyphosate tolerant creeping bentgrass out of the question



Hello every one,
I was contacted by people who would like help in submitting comments. I have prepared something quick below. Once the comment is posted it may be a problem to read because the browsers regard the comments to be pop ups! sincerely, Joe
go to:http://www.regulations.gov/fdmspublic-bld61/component/main
scroll down to animal and plant health inspection service then submit
click on :APHIS-2005-0029
Title Environmental Impact Statement; Petition for Deregulation of Genetically Engineered

Glyphosate-Tolerant Creeping Bentgrass Type NONRULE APHIS Docket ID 03-101-4 scroll down then click on submit comment. Reading the comment when it is posted may be tricky because the browsers view it as a "pop up" . Make sure that the pop-up blocker for the site
is set for pop ups OK.
jcummins wrote:

http://www.i-sis.org.uk/DGTCBOQ.phpISIS Press Release 07/11/05
Deregulation of Glyphosate Tolerant Creeping Bentgrass Out of Question
This article has been submitted to the USDA on behalf of the Independent Science Panel
Professor Joe Cummins
The Animal and Plant Health Inspection Service (APHIS) of the US Department of Agriculture (USDA) received a petition 03-104-01p from Monsanto company and Scotts company on 14 April 2003 requesting deregulation of creeping bent grass genetically modified for tolerance to the herbicide glyphosate. On 5 January 2004, APHIS solicited public comments on whether the modified creeping bentgrass would present a plant pest risk. A preliminary environmental review was prepared by APHIS, and on 12 October 2005, APHIS requested additional information on APHIS Docket ID 03-101-4: Environmental Impact Statement; Petition for Deregulation of Genetically Engineered Glyphosate-Tolerant Creeping Bentgrass. Public comments are due by 14 November 2005: http://www.regulations.gov/fdmspublic-bld61/component/main

Roundup Ready creeping bent grass is tolerant to the herbicide glyphosate. It contains a gene conferring tolerance to the herbicide similar to Roundup Ready maize, soybean, canola, sugar beet or alfalfa. The resistance gene is a synthetic approximation of the 5-enolpyruvyshikimate-3 phosphate synthase from Agrobacterium sp. Strain CP4 (CP4EPSPS), which is preceded by the Arabidopsis chloroplast transit sequence which is required to direct the CP4ESPS to the chloroplast. Transcription is driven by the rice actin promoter and first intron, and terminated by nos 3 from Agrobacterium . A second identical CP4EPSPS sequence is driven by the CaMV promoter with duplicate enhancers, the heat shock 70 intron, and terminated by the nos3 sequence from Agrobacterium . Finally the insert contains nopaline antibiotic resistance gene. Duplicate copies of the herbicide tolerance gene ensure a high level of tolerance to glyphosate [1].

APHIS' preliminary risk assessment concluded that genetically modified (GM) creeping bent grass is phenotypicaly equivalent to unmodified grass. The GM grass had a single insert of the duplicate CP4EPSPS gene, which behaved as a simple Mendelian locus in crosses. The GM creeping bent grass does not differ in susceptibility or resistance to pests and diseases from its unmodified parent. However, the evidence was clear that hybrids with natural grass species were found and most of them were fertile. Herbicide tolerant creeping bent grass or its hybrids could be established in various urban to rural and natural areas [2].

APHIS asked The Weed Society of America, an industry-oriented academic organization, to evaluate the release of herbicide tolerant creeping bent grass in various crop and non-crop ecosystems. The report prepared on behalf of the society concluded that off-site movement of GM creeping bent grass was inevitable, but that the GM grass or its hybrids could be controlled using herbicides other than glyphosate [3]. A study of gene flow from GM creeping bent grass showed that most of the gene flow occurred within 2 km of the field in which the GM grass was grown, but could extend to 14 and 24 km [4]. Inter-specific hybridization between creeping bent grass and related grass species occurred at frequencies as high as six hybrids per thousand plants [5]. Clippings from treated GM creeping bent grass stands were toxic to unmodified grasses, and such clippings will require special handling [6].

The impact of expanded urban and natural area use of glyphosate was hardly discussed in the petition for deregulation and environmental assessment, but that discussion was crucial and should have been included. Glyphosate is toxic to human placental cells within 18 hr at concentrations lower than recommended agricultural use, and Roundup more so than glyphosate. Surprisingly, Roundup was always more toxic than its active ingredient. The glyphosate-based herbicide disrupts aromatase activity and mRNA levels and interacts with the active site of the purified enzyme, and the effects of glyphosate are facilitated by the Roundup formulation in microsomes or in cell culture. The authors of the study conclude that endocrine and toxic effects of Roundup, not just glyphosate, can be observed in mammals [7]. Relyea and his co-workers have documented the devastating impact of Roundup herbicide on amphibian communities in a series of reports [8-10]. Ho and Cummins have reviewed the problems associated with Roundup resistant weeds and the many human and animal health impacts including liver damage, cancers, neuro-defects and spontaneous abortion [11, 12].

The clear evidence of extensive gene flow and hybridization of glyphosate tolerant creeping bent grass, the growing problems of glyphosate resistant weeds plus the new evidence of glyphosate and Roundup toxicity to humans and lethality to amphibians should make any further release of glyphosate tolerant creeping bent grass out of the question, let alone its deregulation.

References
Nelson E and Stone T. Petition for determination of non-regulated status: Roundup Ready Creeping Bent grass Event ASR368 Petition #01-TR-054U 2003 http://www.aphis.usda.gov/brs/not_reg.html

USDA/APHIS APHIS Preliminary Risk Assessment on the Petition for a Determination of Nonregulated Status for Creeping Bentgrass (Agrostis stolonifera) Genetically Engineered (Event ASR368) for Tolerance to the Herbicide Glyphosate submitted by Monsanto Company and the Scotts Company. 2004 http://www.aphis.usda.gov/brs/not_reg.html

Banks P, Branham B, Harrison K, Whitson . and Heap I. Determination of the Potential Impact from the Release of Glyphosate- and Glufosinate-Resistant Agrostis stolonifera L. in Various Crop and Non-Crop Ecosystems Weeds Society of America Report to USDA/APHIS 2003.

Watrud LS, Lee EH, Fairbrother A, Burdick C, Reichman JR, Bollman M, Storm M, King G and Van de Water PK. Evidence for landscape-level, pollen-mediated gene flow from genetically modified creeping bentgrass with CP4 EPSPS as a marker. Proc Natl Acad Sci USA 2004, 101(40),14533-8.

Belanger F, Meagher T, Day P, Plumley K and Meye W. Interspecific hybridization between Agrostis stolonifera and related Agrostis species under field conditions Crop Science 2003, 43, 240-6.

Goss R, Gaussoin R. and Martin A. Phytotoxicity of clippings from creeping bent grass treated with glyphosate. Weed Technology 2004,18, 575-9.

Richard S, Moslemi S, Sipahutar H, Benachour N and Seralini GE. Differential effects of glyphosate and roundup on human placental cells and aromatase. Environ Health Perspect. 2005, 113(6), 716-20.

Relyea, Rick A., Schoeppner, Nancy M., Hoverman, Jason T. Pesticides and amphibiums : the importance of community context. Ecological Applications 2005, 15, 1125–34.

Relyea, Rick A. The lethal impact of roundup on aquatic and terrestial amphibiums. Ecological Applications : 2005, 15, 1118–24.

Relyea, Rick A. The impact of insecticides and herbicides on the biodiversity and productivity of aquatic communities . Ecological Applications 2005,15, 618–27.

HoMW and Cummins,J. Roundup ready sudden death, super weeds, allergens ISIS 2005 http://www.i-sis.org.uk

Ho MW and Cummins,J. Glyphosate toxic and roundup worse. Science in Society 2005, 26, 12. http://www.i-sis.org.uk/isisnews.php


The Institute of Science in Society, PO Box 32097, London NW1 OXR
telephone: [44 20 8643 0681] [44 20 7383 3376] [44 20 7272 5636]

General Enquiries sam@i-sis.org.uk - Website/Mailing List press-release@i-sis.org.uk - ISIS Director m.w.ho@i-sis.org.uk

MATERIAL ON THIS SITE MAY BE REPRODUCED IN ANY FORM WITHOUT PERMISSION, ON CONDITION THAT IT IS ACCREDITED ACCORDINGLY AND CONTAINS A LINK TO http://www.i-sis.org.uk/

********************************************************
To unsubscribe from SANET-MG:
1- Visit http://lists.sare.org/archives/sanet-mg.html to unsubscribe or;
2- Send a message to <listserv@sare.org> from the address subscribed to the list. Type "unsubscribe sanet-mg" in the body of the message.

Visit the SANET-MG archives at: http://lists.sare.org/archives/sanet-mg.html For more information on grants and other resources available through the SARE program, please visit http://www.sare.org.

********************************************************
To unsubscribe from SANET-MG:
1- Visit http://lists.sare.org/archives/sanet-mg.html to unsubscribe or;
2- Send a message to <listserv@sare.org> from the address subscribed to the list. Type "unsubscribe sanet-mg" in the body of the message.

Visit the SANET-MG archives at: http://lists.sare.org/archives/sanet-mg.html
For more information on grants and other resources available through the SARE program, please visit http://www.sare.org.