Sorted by first author.
1. 1989 Circularly permuted proteins. Protein Eng. 2:493-495.
2. Aboulela, F., Nikonowicz, E.P., and Pardi, A. 1994 Distinguishing between duplex and hairpin forms of RNA by N-15-H-1 heteronuclear NMR. FEBS Lett. 347:261-264.
3. Akobashi, E., Guerrier-Takada, C., and Altman, S. 1980 Veal heart ribonuclease P has an essential RNA component. Biochem. Biophys. Res. Comm. 96:831-837.
4. Alifano, P., Rivellini, F., Piscitelli, C., Arraiano, C.M., Bruni, C.B., and Carlomagno, M.S. 1994 Ribonuclease E provides substrates for ribonuclease P- dependent processing of a polycistronic mRNA. Gene. Develop. 8:3021-3031.
5. Allen, K. and Haydock, L.C. 1985 Molecular mechanism of catalysis by RNA. Prog. Clin. Biol. Res. 172A:87-98.
6. Altman, S. and Smith, J.D. 1971 Tyrosine tRNA precursor molecule polynucleotide sequence. Nature New Biol. 233:35-39.
7. Altman, S. 1984 Aspects of biochemical catalysis. Cell 36:237-239.
8. Altman, S., Baer, M., Geurrier-Takada, C., and Vioque, A. 1986 Enzymatic cleavage of RNA by RNA. Trends in Biochem. Sci. 11:515-518.
9. Altman, S.a.C.G.-T. 1986 M1RNA, the RNA subunit of Escherichia coli ribonuclease P, can undergo a pH-sensitive conformational change. Biochemistry 25:1205-1208.
10. Altman, S. 1989 Ribonuclease P: An enzyme with a catalytic RNA subunit. Adv. Enzymol. Relat. Areas Mol. Biol. 62:1-36.
11. Altman, S., Baer, M.F., Bartkiewicz, M., Gold, H., Guerrier, T.C., Kirsebom, L.A., Lumelsky, N., and Peck, K. 1989 Catalysis by the RNA subunit of RNase P - a minireview. Gene 82:63-64.
12. Altman, S. 1990 Nobel lecture. Enzymatic cleavage of RNA by RNA. Biosci. Rep. 10:317-337.
13. Altman, S. 1990 Ribonuclease P. Postscript. J. Biol. Chem. 265:20053-20056.
14. Altman, S., Kirsebom, L., and Talbot, S. 1993 Recent studies of ribonuclease P. FASEB J. 7:7-14.
15. Altman, S. 1993 RNA enzyme-directed gene therapy. Proc. Natl. Acad. of Sci. USA 90:10898-10900.
16. Altman, S., Wesolowski, D., and Puranam, R.S. 1993 Nucleotide sequences of the RNA subunit of RNase P from several mammals. Genomics 18:418-422.
17. Antao, V.P., Lai, S.Y., and Tinoco, I.J. 1991 A thermodynamic study of unusually stable RNA and DNA hairpins. Nucleic Acids Res. 19:5901-5905.
18. Antao, V.P. and Tinoco, I.J. 1992 Thermodynamic parameters for loop formation in RNA and DNA hairpin tetraloops. Nucleic Acids Res. 20:819-824.
19. Apirion, D. 1980 Genetic mapping and some characterization of the rnpA49 mutation of Escherichia coli that affects the RNA-processing enzyme ribonuclease P. Genetics 94:291-299.
20. Apirion, D. and Watson, N. 1980 A second gene which affects the RNA processing enzyme ribonuclease P of Escherichia coli. FEBS Lett.ers 110:161-163.
21. Apirion, D. and Miczak, A. 1993 RNA processing in prokaryotic cells. Bioessays 15:113-120.
22. Armbruster, D., E. S. Haas, J. W. Brown, and C. J. Daniels. 1993 Unpublished data.
23. Arnez, J.G. and Steitz, T.A. 1994 Crystal structure of unmodified tRNA(Gln) complexed with glutaminyl-tRNA synthetase and ATP suggests a possible role for pseudo-uridines in stabilization of RNA structure. Biochemistry 33:7560-7567.
24. Aurup, H., Siebert, A., Benseler, F., Williams, D., and Eckstein, F. 1994 Translation of 2'-modified mRNA in vitro and in vivo. Nucleic Acids Res 22:4963-4968.
25. Ausubel, F.M., Brent, R., Kingston, R.E., Moore, D.D., Seidman, J.G., Smith, J.A., and Struhl, K., Current Protocols in Molecular Biology. 1 ed. Vol. 1 and 2. 1989, New York: John Wiley and Sons.
26. Baer, M. and Altman, S. 1985 A catalytic RNA and its gene from Salmonella typhimurium. Science 228:999-1002.
27. Baer, M.F., Reilly, R.M., McCorkle, G.M., Hai, T.Y., Altman, S., and RajBhandary, U.L. 1988 The recognition by RNase P of precursor tRNAs. J. Biol. Chem. 263:2344-2351.
28. Baer, M.F., Wesolowski, D., and Altman, S. 1989 Characterization in vitro of the defect in a temperature-sensitive mutant of the protein subunit of RNase P from Escherichia coli. J. Bacteriol. 171:6862-6866.
29. Baer, M.F., Arnez, J.G., Guerrier, T.C., Vioque, A., and Altman, S. 1990 Preparation and characterization of RNase P from Escherichia coli. Methods Enzymol.
30. Baer, M., Nilsen, T.W., Costigan, C., and Altman, S. 1990 Structure and transcription of a human gene for H1 RNA, the RNA component of human RNase P. Nucleic Acids Res. 18:97-103.
31. Baier, G., Coggeshall, K.M., Baierbitterlich, G., Giampa, L., Telford, D., Herbert, E., Shih, W., and Altman, A. 1994 Construction and characterization of lck- and fyn-specific tRNA:ribozyme chimeras. Mol Immunol 31:923-932.
32. Banerjee, A.R., Jaeger, J.A., and Turner, D.H. 1993 Thermal unfolding of a group I ribozyme: the low-temperature transition is primarily disruption of tertiary structure. Biochemistry 32:153-163.
33. Banta, A.B., Haas, E.S., Brown, J.W., and Pace, N.R. 1992 Sequence of the ribonuclease P RNA gene from the cyanobacterium Anacystis nidulans. Nucleic Acids Res. 20:911.
34. Bartkiewicz, M., Gold, H., and Altman, S. 1989 Identification and characterization of an RNA molecule that copurifies with RNase P activity from HeLa cells. Genes. Dev. 3:488-499.
35. Baur, C.P. and Knippers, R. 1988 Protein-induced bending of the simian virus 40 origin of replication. J. Mol. Biol. 203:1009-1019.
36. Baur, C.P., Klausing, K., Scheffner, M., Stahl, H., and Knippers, R. 1988 Protein-DNA interactions at the simian virus 40 origin of replication. Biochim. Biophys. Acta. 951:2-3.
37. Beebe, J.A. and Fierke, C.A. 1994 A kinetic mechanism for cleavage of precursor tRNA(Asp) catalyzed by the RNA component of bacillus subtilis ribonuclease p. Biochemistry 33:10294-10304.
38. Behlen, L.S., Sampson, J.R., DiRenzo, A.B., and Uhlenbeck, O.C. 1990 Lead-catalyzed cleavage of yeast tRNAPhe mutants. Biochemistry 29:2515-2523.
39. Belfort, M., Pedersen, L.J., Ehrenman, K., Chu, F.K., Maley, G.F., Maley, F., McPheeters, D.S., and Gold, L. 1986 RNA splicing and in vivo expression of the intron-containing td gene of bacteriophage T4. Gene 41:93-102.
40. Bennett, J.L., Jeong, Y.S., and Clayton, D.A. 1992 Characterization of a Xenopus laevis ribonucleoprotein endoribonuclease. Isolation of the RNA component and its expression during development. J. Biol. Chem. 267:21765-21772.
41. Bevilacqua, P.C., Li, Y., and Turner, D.H. 1994 Fluorescence-detected stopped flow with a pyrene labeled substrate reveals that guanosine facilitates docking of the 5' cleavage site into a high free energy binding mode in the tetrahymena ribozyme. Biochemistry 33:11340-11348.
42. Biswas, T.K. 1991 In vitro transcription analysis of the region of Saccharomyces cerevisiae mitochondrial DNA containing the tRNA(fMet) gene. Nucleic Acids Res. 19:5937-5942.
43. Boehm, S. 1987 Similarities between a predicted secondary structure for the M1 RNA ribozyme and the tRNA binding center of 16 S rRNA from E. coli. FEBS Lett. 220:283-287.
44. Both, V., Moiseyev, G.P., and Sevcik, J. 1991 Specificity of guanylic RNases to polynucleotide substrates. Biochem. Biophys. Res. Commun. 177:630-635.
45. Bothwell, A.L.M., Garber, R.L., and Altman, S. 1976 Nucleotide sequence and in vitro processing of a precursor molecule to Escherichia coli 4.5S RNA. J. Biol. Chem. 251:7709-7716.
46. Bothwell, A.L.M., Stark, B.C., and Altman, S. 1976 Ribonuclease P substrate specificity : Cleavage of a bacteriophage ø80-induced RNA. Proc. Natl. Acad. Sci. USA 73:1912-1916.
47. Bourgaize, D.B. and Fournier, M.J. 1987 Initiation of translation is impaired in E. coli cells deficient in 4.5S RNA. Nature 325:281-284.
48. Brown, R.S., Dewan, J.C., and Klug, A. 1985 Crystallographic and biochemical investigation of the lead(II)- catalyzed hydrolysis of yeast phenylalanine tRNA. Biochemistry 24:4785-4801.
49. Brown, J.W., Hunt, D.A., and Pace, N.R. 1990 Nucleotide sequence of the 10Sa RNA gene of the beta -purple eubacterium Alcaligenes eutrophus. Nucleic Acids Res. 18:2820.
50. Brown, J.W. and Pace, N.R. 1991 Structure and evolution of ribonuclease P RNA. Biochimie 73:689-697.
51. Brown, J.W., Haas, E.S., James, B.D., Hunt, D.A., and Pace, N.R. 1991 Phylogenetic analysis and evolution of RNase P RNA in proteobacteria [published erratum appears in J Bacteriol 1991 Nov;173(21):7063]. J. Bacteriol. 173:3855-3863.
52. Brown, J.W. and Pace, N.R. 1992 Ribonuclease P RNA and protein subunits from Bacteria. Nucleic Acids Res. 20:1451-1456.
53. Brown, J.W., Haas, E.S., and Pace, N.R. 1993 Characterization of ribonuclease P RNAs from thermophilic bacteria. Nucleic Acids Res. 21:671-679.
54. Brown, J.W., Haas, E.S., Gilbert, D.G. and N.R. Pace. 1994 The ribonuclease P database. Nucl. Acids Res. in press.
55. Brown, J.W., J.M. Nolan, E.S. Haas, M.A. Rubio, F. Major and N.R. Pace. 1994 (submitted).
56. Brown, J.W., Haas, E.S., Gilbert, D.G., and Pace, N.R. 1994 The ribonuclease p database. Nucleic Acids Res 22:3660-3662.
57. Buchwalder, A., Szadkowski, H., and Kirschner, K. 1992 A Fully Active Variant of Dihydrofolate-Reductase with a Circularly Permuted Sequence. Biochemistry 31:1621-1630.
58. Burgin, A.B. and Pace, N.R. 1990 Mapping the active site of ribonuclease P RNA using a substrate containing a photoaffinity agent. EMBO J. 9:4111-4118.
59. Burkard, U. and Söll, D. 1988 The unusually long amino acid acceptor stem of Escherichia coli selenocysteine tRNA results from abnormal cleavage by RNase P. Nucleic Acids Res. 16:11617-11624.
60. Burkard, U. and Söll, D. 1988 The 5'-terminal guanylate of chloroplast histidine tRNA is encoded in its gene. J. Biol. Chem. 263:9578-9581.
61. Burkard, U., Willis, I., and Söll, D. 1988 Processing of histidine transfer RNA precursors. Abnormal cleavage site for RNase P. J. Biol. Chem. 263:2447-2451.
62. Burke, J.M., Belfort, M., Cech, T.R., Davies, R.W., Schweyen, R.J., Shub, D.A., Szostak, J.W., and Tabak, H.F. 1987 Structural conventions for group I introns. Nucleic Acids Res. 15:7217-7221.
63. Burrows, C.J. and Rokita, S.E. 1994 Recognition of guanine structure in nucleic acids by nickel complexes. Account. Chem. Res. 27:295-301.
64. Butcher, S.E. and Burke, J.M. 1994 Structure-mapping of the hairpin ribozyme - magnesium- dependent folding and evidence for tertiary interactions within the ribozyme-substrate complex. J. Mol. Biol. 244:52-63.
65. Caddle, M.S., Dailey, L., and Heintz, N.H. 1990 RIP60, a mammalian origin-binding protein, enhances DNA bending near the dihydrofolate reductase origin of replication. Mol. Cell. Biol. 10:6236-6243.
66. Calcutt, M.J. and Schmidt, F.J. 1992 Conserved gene arrangement in the origin region of the Streptomyces coelicolor chromosome. J. Bacteriol. 174:3220-3226.
67. Caprara, M.G. and Waring, R.B. 1994 Deletion of p9 and stem-loop structures downstream from the catalytic core affects both 5' and 3' splicing activities in a group-I intron. Gene 143:29-37.
68. Carrara, G., Calandra, P., Fruscoloni, P., Doria, M., and Tocchini, V.G. 1989 Site selection by Xenopus laevis RNAase P. Cell 58:37-45.
69. Carrara, G., Calandra, P., Fruscoloni, P., and Tocchini-Valentini, G.P. 1995 Two helices plus a linker: A small model substrate for eukaryotic RNase P. Proc. Natl. Acad. Sci., USA 92:2627-2631.
70. Carter, B.J., Vold, B.S., and Hecht, S.M. 1990 Control of the position of RNase P-mediated transfer RNA precursor processing. J. Biol. Chem. 265:7100-7103.
71. Castano, J.G., Ornber, R., Koster, J.G., Toblon, J.A., and Zaslof, M. 1986 Eukaryotic Pre-tRNA 5' processing Nuclease: Copurification with a complex cylindrical particle. Cell 46:377-387.
72. Castanotto, D., Rossi, J.J., and Deshler, J.O. 1992 Biological and functional aspects of catalytic RNAs. Crit. Rev. Eukaryot. Gene. Expr. 2:331-357.
73. Cech, T.R. and Bass, B.L. 1986 Biological catalysis by RNA. Annu. Rev. Biochem. 55:
74. Cech, T.R. 1993 The Efficiency and Versatility of Catalytic RNA - Implications for an RNA World. Gene 135:33-36.
75. Cech, T.R., Structure and mechanism of the large catalytic RNAs: group I and group II introns and ribonuclease P, in The RNA World, R.F.G.a.J.F. Atkins, Editor. 1993, Cold Spring Harbor Laboratory Press: Cold Spring Harbor, NY. p. 239-269.
76. Cech, T.R., Damberger, S.H., and Gutell, R.R. 1994 Representation of the secondary and tertiary structure of group I introns. Nature Struct. Biology 1:273-280.
77. Cedergren, R., Lang, B.F., and Gravel, D. 1988 The relationship between RNA catalytic processes. Orig. Life Evol Biosph 18:299-305.
78. Cedergren, R., Gautheret, D., Lapalme, G., and Major, F. 1988 A secondary and tertiary structure editor for nucleic acids. Comput. Appl. Biosci. 4:143-146.
79. Chang, K.Y. and Tinoco, I. 1994 Characterization of a ''kissing'' hairpin complex derived from the human immunodeficiency virus genome. Proc Natl Acad Sci Usa 91:8705-8709.
80. Charlebois, R.L., Schalkwyk, L.C., Hofman, J.D., and Doolittle, W.F. 1991 Detailed physical map and set of overlapping clones covering the genome of the archaebacterium Haloferax volcanii DS2. J. Mol. Biol. 222:509-524.
81. Cherayil, B., Krupp, G., Schuchert, P., Char, S., and Söll, D. 1987 The RNA components of Schizosaccharomyces pombe RNase P are essential for cell viability. Gene 60:157-161.
82. Ciesiolka, J., Hardt, W.D., Schlegl, J., Erdmann, V.A., and Hartmann, R.K. 1994 Lead-Ion-Induced Cleavage of RNase P RNA. Eur. J. Biochem. 219:49-56.
83. Clark, J.M. 1988 Novel non-templated nucleotide addition reactions catalyzed by procaryotic and eucaryotic DNA polymerases. Nucleic Acids Res. 16:9677-9686.
84. Corpet, F. and Michot, B. 1994 RNAlign program: alignment of RNA sequences using both primary and secondary structures. Comput. Appl. Biosci. 10:389-399.
85. Craft, J. and Gold, H. 1990 New RNPs of higher eukaryotes. Mol. Biol. Rep. 14:97-101.
86. Craft, J. and Gold, H. 1990 The Th ribonucleoprotein particle: association with the RNA processing enzymes RNase MRP and RNase P. Mol. Biol. Rep. 14:109.
87. Cunningham, P.R. and Ofengand, J. 1990 Use of inorganic pyrophosphatase to improve the yield of in vitro transcription reactions catalyzed by T7 RNA polymerase. Biotechniques 9:713-714.
88. Cunningham, P.R., Weitzmann, C.J., and Ofengand, J. 1991 SP6 RNA polymerase stutters when initiating from an AAA... sequence. Nucleic Acids Res. 19:4669-4673.
89. Cunningham, P.R., Richard, R.B., Weitzmann, C.J., Nurse, K., and Ofengand, J. 1991 The absence of modified nucleotides affects both in vitro assembly and in vitro function of the 30S ribosomal subunit of Escherichia coli. Biochimie 73:789-796.
90. Dahm, S.C., Derrick, W.B., and Uhlenbeck, O.C. 1993 Evidence for the role of solvated metal hydroxide in the hammerhead cleavage mechanism. Biochemistry 32:13040-13045.
91. Dallmann, G., Quinn, T., and Apirion, D. 1983 A gene affecting the accumulation of the RNA moiety of the processing enzyme RNase P. J. Bacteriol. 156:529-536.
92. Dang, Y.L. and Martin, N.C. 1993 Yeast mitochondrial RNase P. Sequence of the RPM2 gene and demonstration that its product is a protein subunit of the enzyme. J. Biol. Chem. 268:19791-19796.
93. Daros, J.A., Marcos, J.F., Hernandez, C., and Flores, R. 1994 Replication of avocado sunblotch viroid: evidence for a symmetric pathway with two rolling circles and hammerhead ribozyme processing. Proc. Natl. Acad. Sci. USA 91:12813-12817.
94. Darr, S.C., Pace, B., and Pace, N.R. 1990 Characterization of ribonuclease P from the archaebacterium Sulfolobus solfataricus. J. Biol. Chem. 265:12927-12932.
95. Darr, S.C., Brown, J.W., and Pace, N.R. 1992 The varieties of ribonuclease P. Trends Biochem. Sci. 17:178-182.
96. Darr, S.C., Zito, K., Smith, D., and Pace, N.R. 1992 Contributions of phylogenetically variable structural elements to the function of the ribozyme ribonuclease P. Biochemistry 31:328-333.
97. Davies, R.W., Waring, R.B., Ray, J.A., Brown, T.A., and Scazzocchio, C. 1982 Making ends meet: a model for RNA splicing in fungal mitochondria. Nature 300:719-724.
98. Delp, G., Igloi, G.L., and Kossel, H. 1991 Identification of in vivo processing intermediates and of splice junctions of tRNAs from maize chloroplasts by amplification with the polymerase chain reaction. Nucleic Acids Res. 19:713-716.
99. Deyoung, M.B., Kincadedenker, J., Boehm, C.A., Riek, R.P., Mamone, J.A., McSwiggen, J.A., and Graham, R.M. 1994 Functional characterization of ribozymes expressed using U1 and T7 vectors for the intracellular cleavage of ANF mRNA. Biochemistry 33:12127-12138.
100. Dieckmann, T. and Feigon, J. 1994 Heteronuclear techniques in NMR studies of RNA and DNA. Curr. Opin. Struct. Biol. 4:745-749.
101. Doerson, C., C., G.-T., Altman, S., and Attardi, G. 1985 Characterization of RNase P from HeLa Cell mitochondria; comparison with the cytosol RNase P Activity. J. Biol. Chem. 260:5942-5949.
102. Dong, X., Rouillard, K.P., Womble, D.D., and Rownd, R.H. 1989 DNA bending near the replication origin of IncFII plasmid NR1. J. Bacteriol. 171:703-707.
103. Doolittle, W.P., and J.R. Brown. 1994 Tempo, mode, the progenote, and the universal root. Proc. Natl. Acad. Sci. USA 91:6721-6728.
104. Doria, M., Carrara, G., Calandra, P., and Tocchini-Valentini, G.P. 1991 An RNA molecule copurifies with RNase P activity from Xenopus laevis oocytes. Nucleic Acids Res. 19:2315-2320.
105. Drainas, D., Zimmerly, S., Willis, I., and Söll, D. 1989 Substrate structural requirements of Schizosaccharomyces pombe RNase P. FEBS Lett. 251:1-2.
106. Draper, D.E., White, S.A., and Kean, J.M. 1988 Preparation of specific ribosomal RNA fragments. Methods Enzymol. 164:221-237.
107. Dubendorff, J.W. and Studier, F.W. 1991 Creation of a T7 autogene. Cloning and expression of the gene for bacteriophage T7 RNA polymerase under control of its cognate promoter. J. Mol. Biol. 219:61-68.
108. Dunn, J.J. and Studier, F.W. 1983 Nucleotide sequence of T7 DNA. J. Mol. Biol. 166:477-535.
109. Eisen, H. 1988 RNA editing : who's on first? Cell 53:331-332.
110. Elferink, C.J. and Whitlock, J.J. 1990 2,3,7,8-Tetrachlorodibenzo-p-dioxin-inducible, Ah receptor-mediated bending of enhancer DNA. J. Biol. Chem. 265:5718-5721.
111. Ellington, A.D. 1993 Experimental testing of theories of an early RNA world. Molecular Evolution: Producin
112. Emerick, V.L. and Woodson, S.A. 1994 Fingerprinting the folding of a group I precursor RNA. Proc. Natl. Acad. Sci. USA 91:9675-9679.
113. Engelke, D.R., Gegenheimer, P., and Ableson, J. 1985 Nuceolytic Processing of a tRNAarg -tRNAasp Dimeric precursor by a homologous component from Saccharomyces cerevisiae. J. Biol. Chem. 260:1271-1279.
114. England, T.E., Bruce, A.G., and Uhlenbeck, O.C. 1980 Specific labeling of 3' termini of RNA with T4 RNA ligase. Methods Enzymol. 65:65-74.
115. Evans, C.F. and Engelke, D.R. 1991 Binding of yeast TFIIIC to tRNA gene bipartite internal promoters: Analysis of physical effects on the intervening DNA. Biochem. Biophys. Res. Commun. 176:826-832.
116. Forster, A.C. and Altman, S. 1990 External guide sequences for an RNA enzyme. Science 249:783-786.
117. Forster, A.C. and Altman, S. 1990 Similar cage-shaped structures for the RNA components of all ribonuclease P and ribonuclease MRP enzymes. Cell 62:407-409.
118. Frank, D.F., Roiha, H., and Guthrie, C. 1994 Architecture of the U5 Small Nuclear RNA. Mol. Cell. Biol. 14:2180-2190.
119. Frank, D.N., Harris, M.E., and Pace, N.R. 1994 Rational design of self-cleaving pre-tRNA ribonuclease P RNA conjugates. Biochemistry 33:10800-10808.
120. Franzen, J.S., Zhang, M.C., Chay, T.R., and Peebles, C.L. 1994 Thermal activation of a group II intron ribozyme reveals multiple conformational states. Biochemistry 33:11315-11326.
121. Fu, D.J., Rajur, S.B., and Mclaughlin, L.W. 1994 Activity of the hammerhead ribozyme upon inversion of the stereocenters for the guanosine 2'-hydroxyls. Biochemistry 33:13903-13909.
122. Fujita, M., Yoshikawa, H., and Ogasawara, N. 1989 Structure of the dnaA region of Pseudomonas putida: Conservation among three bacteria, Bacillus subtilis, Escherichia coli and P. putida. Mol. Gen Genet 215:381-387.
123. Fujita, M., Yoshikawa, H., and Ogasawara, N. 1990 Structure of the dnaA region of Micrococcus luteus: conservation and variations among eubacteria. Gene 93:73-78.
124. Fujita, M.Q., Yoshikawa, H., and Ogasawara, N. 1992 Structure of the dnaA and DnaA-box region in the Mycoplasma capricolum chromosome: conservation and variations in the course of evolution. Gene
125. Furdon, P.J., Guerrier-Takada, C., and Altman, S. 1983 A G43 to U43 mutation in E. coli tRNA super(Tyr)su sub(3) super(+) which affects processing by RNase P. Nucleic Acids Res. 11:1491-1505.
126. Garber, R.L. and Altman, S. 1979 In vitro processing of B. mori transfer RNA precursor molecules. Cell 17:389-397.
127. Gardiner, K. and Pace, N.R. 1980 RNase P of Bacillus subtilis has an RNA component. J. Biol. Chem. 255:7507-7509.
128. Gardiner, K.J., Marsh, T.L., and Pace, N.R. 1985 Ion dependence of the Bacillus subtilis RNase P reaction. J. Biol. Chem. 260:5415-5419.
129. Gaur, R.K. and Krupp, G. 1993 Modification interference approach to detect ribose moieties important for the optimal activity of a ribozyme. Nucleic Acids Res. 21:21-26.
130. Gauss, D.H., Gruter, F., and Sprinzl, M., Compilation of tRNA sequences, in Transfer RNA: Structure, Properties, and Recognition, D.S.a.J.N.A. P.R. Schimmel, Editor. 1979, Cold Spring Harbor Laboratory: Cold Spring Harbor, NY. p. 518-519.
131. Gautheret, D., Major, F., and Cedergren, R. 1990 Pattern searching/alignment with RNA primary and secondary structures: an effective descriptor for tRNA. Comput. Appl. Biosci. 6:325-331.
132. Gautheret, D., Major, F., and Cedergren, R. 1990 Computer modeling and display of RNA secondary and tertiary structures. Methods Enzymol. 318-330.
133. Gautheret, D., Major, F., and Cedergren, R. 1993 Modeling the three-dimensional structure of RNA using discrete nucleotide conformational sets. J. Mol. Biol. 229:1049-1064.
134. Gmeiner, W.H., Anderson, J., and Sahasrabudhe, P. 1994 NMR studies show monomeric 5-fluorouridine forms base pairs of increased stability compared with uridine in non- aqueous solvents. Nucleos. Nucleot. 13:2329-2344.
135. Gold, H.A. and Altman, S. 1986 Reconstitution of RNAase P activity using inactive subunits from E. coli and HeLa cells. Cell 44:243-249.
136. Gold, H.A., Craft, J., Hardin, J.A., Bartkiewicz, M., and Altman, S. 1988 Antibodies in human serum that precipitate ribonuclease P. Proc. Natl. Acad. Sci. USA 85:5483-5487.
137. Gold, H.A., Topper, J.N., Clayton, D.A., and Craft, J. 1989 The RNA processing enzyme RNase MRP is identical to the Th RNP and related to RNase P. Science 245:1377-1380.
138. Gold, L. 1990 Catalytic RNA: a Nobel Prize for small village science [editorial]. New Biol. 2:1-4.
139. Gold, L., Tuerk, C., allen, P., Binkley, J., Brown, D., Green, L., MacDougal, S., Schneider, D., Tasset, D., and Eddy, S.R., RNA: The Shape of Things to Come, in The RNA World, R.F.G.a.J.F. Atkins, Editor. 1993, Cold Spring Harbor Laboratory Press: Cold Spring Harbor, N.Y. p. 497-510.
140. Green, C.J., Vold, B.S., Morch, M.D., Joshi, R.L., and Haenni, A.L. 1988 Ionic conditions for the cleavage of the tRNA-like structure of turnip yellow mosaic virus by the catalytic RNA of RNase P. J. Biol. Chem. 263:11617-11620.
141. Green, C.J. and Vold, B.S. 1988 Structural requirements for processing of synthetic tRNAHis precursors by the catalytic RNA component of RNase P. J. Biol. Chem. 263:652-657.
142. Green, C.J. and Vold, B.S. 1989 Cleavage of the tRNA-like RNA of the turnip yellow mosaic virus by the catalytic RNA component of RNase P. Molecular Biology of RNA 89-98:
143. Groebe, D.R. and Uhlenbeck, O.C. 1989 Thermal stability of RNA hairpins containing a four-membered loop and a bulge nucleotide. Biochemistry 28:742-747.
144. Guerrier-Takada, C., Gardiner, K., Marsh, T., Pace, N., and Altman, S. 1983 The RNA moiety of ribonuclease P is the catalytic subunit of the enzyme. Cell 35:849-857.
145. Guerrier-Takada, C. and Altman, S. 1984 Catalytic activity of an RNA molecule prepared by transcription in vitro. Science 223:285-286.
146. Guerrier-Takada, C. and Altman, S. 1984 Structure in solution of MI RNA, The catalytic subunit of ribonuclease P from Escherichia coli. Biochemistry 23:6327-6334.
147. Guerrier-Takada, C., McClain, W.H., and Altman, S. 1984 Cleavage of tRNA precursors by the RNA subunit of E. coli ribonuclease P (MI RNA) is influenced by 3'-proximal CCA in the substrates. Cell 38:219-224.
148. Guerrier-Takada, C. and Altman, S. 1986 M1 RNA with large terminal deletions retains its catalytic activity. Cell 45:177-183.
149. Guerrier-Takada, C., Haydock, K., Allen, L., and Altman, S. 1986 Metal ion requirements and other aspects of the reaction catalyzed by M1 RNA, the RNA subunit of ribonuclease P from Escherichia coli. Biochemistry 25:1509-1515.
150. Guerrier-Takada, C., van Belkum, A., Pleij, C.W.A., and Altman, S. 1988 Novel reactions of RNAase P with a tRNA-like structure in turnip yellow mosaic virus RNA. Cell 53:267-272.
151. Guerrier-Takada, C., Lumelsky, N., and Altman, S. 1989 Specific interactions in RNA enzyme-substrate complexes. Science 246:1578-1584.
152. Guerrier-Takada, C. and Altman, S. 1992 Reconstitution of enzymatic activity from fragments of M1 RNA. Proc. Natl. Acad. Sci. USA 89:1266-1270.
153. Guerrier-Takada, C. and Altman, S. 1993 A physical assay for and kinetic analysis of the interactions between M1 RNA and tRNA precursor substrates. Biochemistry 32:7152-7161.
154. Guo, H.C.T. and Collins, R.A. 1995 Efficient trans-cleavage of a stem-loop RNA substrate by a ribozyme derived from Neurospora VS RNA. Embo J 14:368-376.
155. Gurevitz, M., Jain, S.K., and Apirion, D. 1983 Identification of a precursor molecule for the RNA moiety of the processing enzyme RNase P. Proc. Natl. Acad. Sci. USA 80:4450-4454.
156. Gutell, R.R., Power, A., Hertz, G.Z., Putz, E.J., and Stormo, G.D. 1992 Identifying constraints on the higher-order structure of RNA: continued development and application of comparative sequence analysis methods. Nucleic Acids Res. 20:5785-5795.
157. Gutell, R.R., Larsen, N., and Woese, C.R. 1994 Lessons from an Evolving rRNA - 16S and 23S rRNA Structures from a Comparative Perspective. Microbiol. Rev. 58:10-26.
158. Haas, E.S., Morse, D.P., Brown, J.W., Schmidt, F.J., and Pace, N.R. 1991 Long-range structure in ribonuclease P RNA. Science 254:853-856.
159. Haas, E.S., Brown, J.W., Pitulle, C., and Pace, N.R. 1994 Further perspective on the catalytic core and secondary structure of ribonuclease P RNA. Proc. Natl. Acad. Sci. USA 91:2527-2531.
160. Hall, K.B., Sampson, J.R., Uhlenbeck, O.C., and Redfield, A.G. 1989 Structure of an unmodified tRNA molecule. Biochemistry 28:5794-801.
161. Hancock, K., LeBlanc, A.J., Donze, D., and Hajduk, S.L. 1992 Identification of nuclear encoded precursor tRNAs within the mitochondrion of Trypanosoma brucei. J. Biol. Chem. 267:23963-26971.
162. Hanna, M. and Szostak, J.W. 1994 Suppression of mutations in the core of the Tetrahymena ribozyme by spermidine, ethanol and by substrate stabilization. Nucleic Acids Res. 22:5326-5331.
163. Hannon, G.J., Chubb, A., Maroney, P.A., Hannon, G., Altman, S., and Nilsen, T.W. 1991 Multiple cis-acting elements are required for RNA polymerase III transcription of the gene encoding H1 RNA, the RNA component of human RNase P. J. Biol. Chem. 266:22796-22799.
164. Hansen, F.G., Hansen, E.B., and Atlung, T. 1985 Physical mapping and nucleotide sequence of the rnpA gene that encodes the protein component of ribonuclease P in Escherichia coli. Gene 38:85-93.
165. Hardt, W.D., Schlegl, J., Erdmann, V.A., and Hartmann, R.K. 1993 Gel retardation analysis of E. coli M1 RNA-tRNA complexes. Nucleic Acids Res. 21:3521-3527.
166. Hardt, W.D., Schlegl, J., Erdmann, V.A., and Hartmann, R.K. 1993 Role of the D arm and the anticodon arm in tRNA recognition by eubacterial and eukaryotic RNase P enzymes. Biochemistry 32:13046-13053.
167. Harris, M.E., Nolan, J.M., Malhotra, A., Brown, J.W., Harvey, S.C., and Pace, N.R. 1994 Use of photoaffinity crosslinking and molecular modeling to analyze the global architecture of ribonuclease P RNA. EMBO J. 13:3953-3963.
168. Hartmann, R.K. and Erdmann, V.A. 1991 Analysis of the gene encoding the RNA subunit of ribonuclease P from T. thermophilus HB8. Nucleic Acids Res. 19:5957-5964.
169. Hayashi, D.K. and Stark, B.C. 1994 A novel tRNA precursor cleaving endoribonuclease from Zea mays. Arch. Biochem. Biophys. 309:123-128.
170. Haydock, K. and Allen, L.C. 1985 Molecular mechanism of catalysis by RNA.
171. Henikoff, S. 1984 Unidirectional digestion with exonuclease III creates targeted breakpoints for DNA sequencing. Gene 28:351-359.
172. Heus, H.A. and Pardi, A. 1991 Structural features that give rise to the unusual stability of RNA hairpins containing GNRA loops. Science 253:191-194.
173. Hines, J.V., Landry, S.M., Varani, G., and Tinoco, I. 1994 Carbon-proton scalar couplings in RNA: 3D heteronuclear and 2D isotope-edited NMR of a C-13-Labeled extra-stable hairpin. J. Am. Chem. Soc. 116:5823-5831.
174. Hixson, S.H. and Hixson, S.S. 1975 p-Azidophenacyl bromide, a versatile photolabile bifunctional reagent. Reaction with glyceraldehyde-3-phoshate dehydrogenase. Biochemistry 14:4251-4254.
175. Hollingsworth, M.J. and Martin, N.C. 1986 RNase P activity in the mitochondria of Saccharomyces cerevisiae depends on both mitochondrion and nucleus-encoded components. Mol. Cell. Biol. 6:1058-1064.
176. Hollingsworth, M.J. and Martin, N.C. 1987 Alteration of a mitochondrial tRNA precursor 5' leader abolishes its cleavage by yeast mitochondrial RNase P. Nucleic Acids Res. 15:8845-8860.
177. Holm, P.S. and Krupp, G. 1992 The acceptor stem in pre-tRNAs determines the cleavage specificity of RNase P. Nucleic Acids Res. 20:421-423.
178. Homann, M., Tabler, M., Tzortzakaki, S., and Sczakiel, G. 1994 Extension of helix II of an HIV-1-directed hammerhead ribozyme with long antisense flanks does not alter kinetic parameters in vitro but causes loss of the inhibitory potential in living cells. Nucleic Acids Res 22:3951-3957.
179. Hosaka, H., Sakabe, I., Sakamoto, K., Niimi, T., Yokoyama, S., and Takaku, H. 1994 Characterization of the secondary structure of an oligonucleotide corresponding to the autocleavage site of a precursor RNA from bacteriophage t4. Bba. Gene Struct. Express. 1218:351-356.
180. Howe, P., Nagai, K., Neuhaus, D., and Varani, G. 1994 NMR studies of u1 snRNA recognition by the n-terminal RNP domain of the human U1A protein. Embo J 13:3873-3881.
181. Igel, A.H. and Ares, M.J. 1988 Internal sequences that distinguish yeast from metazoan U2 snRNA are unnecessary for pre-mRNA splicing. Nature 334:450-453.
182. Inoue, T. and Cech, T.R. 1985 Secondary structure of the circular form of the Tetrahymena rRNA intervening sequence: a technique for RNA structure analysis using chemical probes and reverse transcriptase. Proc. Natl. Acad. Sci. USA 82:648-652.
183. Jaeger, L., Westhof, E., and Michel, F. 1993 Monitoring of the cooperative unfolding of the sunY group I intron of bacteriophage T4. The active form of the sunY ribozyme is stabilized by multiple interactions with 3' terminal intron components. J. Mol. Biol. 234:331-346.
184. Jaeger, L., Michel, F., and Westhof, E. 1994 Involvement of a GNRA tetraloop in long-range RNA tertiary interactions. J. Mol. Biol. 236:1271-1276.
185. Jain, S.K., Gurevitz, M., and Apirion, D. 1982 A small RNA that complements mutants in the RNA processing enzyme ribonuclease P. J. Mol. Biol. 162:515-533.
186. Jain, S.K., Pragai, B., and Apirion, D. 1982 A possible complex containing RNA processing enzymes. Biochem. Biophys. Res. Commun. 106:768-778.
187. James, B.D., Olsen, G.J., Liu, J., and Pace, N.R. 1988 The secondary structure of ribonuclease P RNA, the catalytic element of a ribonucleoprotein enzyme. Cell 52:19-26.
188. James, B.D., Olsen, G.J., and Pace, N.R. 1989 Phylogenetic comparative analysis of RNA secondary structure. Methods Enzymol. 227-239.
189. Jayanthi, G.P. and Van, T.G. 1992 Characterization of ribonuclease P isolated from rat liver cytosol. Arch. Biochem. Biophys. 296:264-270.
190. Jeoung, Y.H., Kumar, P., Suh, Y.A., Taira, K., and Nishikawa, S. 1994 Identification of phosphate oxygens that are important for self-cleavage activity of the HDV ribozyme by phosphorothioate substitution interference analysis. Nucleic Acids Res 22:3722-3727.
191. Jung, Y.H., Park, I., and Lee, Y. 1992 Alteration of RNA I metabolism in a temperature-sensitive Escherichia coli rnpA mutant strain. Biochem. Biophys. Res. Commun. 186:1463-1470.
192. Kahle, D., Wehmeyer, U., and Krupp, G. 1990 Substrate recognition by RNase P and by the catalytic M1 RNA: identification of possible contact points in pre-tRNAs. EMBO J. 9:1929-1937.
193. Kahle, D., Wehmeyer, U., Char, S., and Krupp, G. 1990 The methylation of one specific guanosine in a pre-tRNA prevents cleavage by RNase P and by the catalytic M1 RNA. Nucleic Acids Res. 18:837-844.
194. Kahle, D., Kust, B., and Krupp, G. 1993 Phosphorothioates in pre-tRNAs can change the specificities of RNAses P or reduce the cleavage efficiencies. Biochimie 75:955-962.
195. Kanavarioti, A. 1994 Template-directed chemistry and the origins of the RNA world. Origins Life Evol. Biosphere 24:479-494.
196. Karwan, R., Bennett, J.L., and Clayton, D.A. 1991 Nuclear RNase MRP processes RNA at multiple discrete sites: interaction with an upstream G box is required for subsequent downstream cleavages. Genes. Dev. 5:1264-1276.
197. Karwan, R. 1993 RNase MRP/RNase P: a structure-function relation conserved in evolution? FEBS Lett. 319:1-4.
198. Katahira, M., Kanagawa, M., Sato, H., Uesugi, S., Fujii, S., Kohno, T., and Maeda, T. 1994 Formation of sheared G:A base pairs in an RNA duplex modelled after ribozymes, as revealed by NMR. Nucleic Acids Res. 22:2752-2759.
199. Kazakov, S. and Altman, S. 1991 Site-specific cleavage by metal ion cofactors and inhibitors of M1 RNA, the catalytic subunit of RNase P from Escherichia coli. Proc. Natl. Acad. Sci. USA 88:9193-9197.
200. Kazakov, S. and Altman, S. 1992 A trinucleotide can promote metal ion-dependent specific cleavage of RNA. Proc. Natl. Acad. Sci. USA 89:7939-7943.
201. Kelly, K.O., Reuven, N.B., Li, Z.W., and Deutscher, M.P. 1992 RNase PH Is Essential for transfer RNA Processing and Viability in RNase-Deficient Escherichia-Coli Cells. J. Biol. Chem. 267:16015-16018.
202. Kikuchi, Y. and Ando, Y. 1989 Molecular cloning of a ribozyme gene of Escherichia coli using polymerase chain reaction (PCR). Agric. Biol. Chem. 53:2005-2008.
203. Kikuchi, Y., Sasaki, N., and Ando, Y.Y. 1990 Cleavage of tRNA within the mature tRNA sequence by the catalytic RNA of RNase P: implication for the formation of the primer tRNA fragment for reverse transcription in copia retrovirus-like particles. Proc. Natl. Acad. Sci. USA 87:8105-8109.
204. Kikuchi, Y. and Sasaki, N. 1992 Hyperprocessing of tRNA by the catalytic RNA of RNase P. Cleavage of a natural tRNA within the mature tRNA sequence and evidence for an altered conformation of the substrate tRNA. J. Biol. Chem. 267:11972-11976.
205. Kikuchi, Y., Sasaki-Tozawa, N., and Suzuki, K. 1993 Artificial self-cleaving molecules consisting of a tRNA precursor and the catalytic RNA of RNase P. Nucl. Acids Res. 21:4685-4689.
206. Kikuchi, Y. and Suzukifujita, K. 1995 Synthesis and self-cleavage reaction of a chimeric molecule between RNase P-RNA and its model substrate. J Biochem Tokyo 117:197-200.
207. Kim, S.H., Quigley, G.J., Suddath, F.L., McPherson, A., Sneden, D., Kim, J.J., Weinzierl, J., and Rich, A. 1973 Three-dimensional structure of yeast phenylalanine transfer RNA: folding of the polynucleotide chain. Science 179:285-288.
208. Kim, S.H., Sussman, J.L., Suddath, F.L., Quigley, G.J., McPherson, A., Wang, A.H., Seeman, N.C., and Rich, A. 1974 The general structure of transfer RNA molecules. Proc. Natl. Acad. Sci. USA 71:4970-4974.
209. Kim, S.H., Suddath, F.L., Quigley, G.J., McPherson, A., Sussman, J.L., Wang, A.H., Seeman, N.C., and Rich, A. 1974 Three-dimensional tertiary structure of yeast phenylalanine transfer RNA. Science 185:435-440.
210. Kimura, T., Asai, T., Imai, M., and Takanami, M. 1989 Methylation strongly enhances DNA bending in the replication origin region of the Escherichia coli chromosome. Mol. Gen. Genet. 219:1-2.
211. Kingsman, A.J. and Kingsman, S.M. 1988 Ty: A retroelement moving forward. Cell 53:333-335.
212. Kirsebom, L.A., Baer, M.F., and Altman, S. 1988 Differential effects of mutations in the protein and RNA moieties of RNase P on the efficiency of suppression by various tRNA suppressors. J. Mol. Biol. 204:879-888.
213. Kirsebom, L.A. and Altman, S. 1989 Reaction in vitro of some mutants of RNase P with wild-type and temperature-sensitive substrates. J. Mol. Biol. 207:837-840.
214. Kirsebom, L.A. and Svard, S.G. 1992 The kinetics and specificity of cleavage by RNase P is mainly dependent on the structure of the amino acid acceptor stem. Nucleic Acids Res. 20:425-432.
215. Kirsebom, L.A. and Svard, S.G. 1993 Identification of a region within M1 RNA of Escherichia coli RNase P important for the location of the cleavage site on a wild-t ype tRNA precursor. J. Mol. Biol. 231:594-604.
216. Kirsebom, L.A. and Svard, S.G. 1994 Base pairing between Escherichia coli RNase P RNA and its substrate. Embo J 13:4870-4876.
217. Kiss, T., Marshallsay, C., and Filipowicz, W. 1992 7-2/MRP RNAs in plant and mammalian cells: association with higher order structures in the nucleolus. EMBO J. 11:3737-3746.
218. Kleineidam, R.G., Pitulle, C., Sproat, B., and Krupp, G. 1993 Efficient cleavage of pre-tRNAs by E. coli RNAse P RNA requires the 2'-hydroxyl of the ribose at the cleavage site. Nucleic Acids Res. 21:1097-1101.
219. Kleinschmidt, J.A., Hugle, B., Grund, C., and W, F.W. 1983 The 22S cylinder particles of Xenopus laevis. I. Biochemical and electron microscopic characterization. Eur. J. Cell Biol 32:143-156.
220. Kline, L., Nishikawa, S., and Söll, D. 1981 Partial Purification of RNase P from Schizosaccharomyces pombe. J. Biol. Chem. 256:5058-5063.
221. Knap, A.K., Wesolowski, D., and Altman, S. 1990 Protection from chemical modification of nucleotides in complexes of M1 RNA, the catalytic subunit of RNase P from E coli, and tRNA precursors. Biochimie 72:779-790.
222. Knitt, D.S., Narlikar, G.J., and Herschlag, D. 1994 Dissection of the role of the conserved G•U pair in group I RNA self-splicing. Biochemistry 33:13864-13879.
223. Kole, R. and Altman, S. 1979 Reconstitution of RNase P Activity from Inactive RNA and Protein. Pro. Natl. Acad. Sci. USA 76:3795- 3799.
224. Kole, R., Baer, M.F., Stark, B.C., and Altman, S. 1980 E. coli RNase P has a required RNA component in vivo. Cell 19:881-887.
225. Kole, R. and Altman, S. 1981 Properties of purified Ribonuclease P from Escherichia coli. Biochemistry 20:
226. Komine, Y. and Inokuchi, H. 1991 Precise mapping of the rnpB gene encoding the RNA component of RNase P in Escherichia coli K-12. J. Bacteriol. 173:1813-1816.
227. Komine, Y., Kitabatake, M., Yokogawa, T., Nishikawa, K., and Inokuchi, H. 1994 A tRNA-like structure is present in 10Sa RNA, a small stable RNA from escherichia coli. Proc. Natl. Acad. Sci. Usa 91:9223-9227.
228. Koski, R.A., Bothwell, A.L.M., and Altman, S. 1976 Identification of a Ribonuclease P-Like Activity from Human KB Cells. Cell 9:101-116.
229. Krupp, G., Cherayil, B., Frendewey, D., Nishikawa, S., and Söll, D. 1986 Two RNA species co-purify with RNase P from the fission yeast Schizosaccharomyces pombe. EMBO J. 5:1697-1703.
230. Krupp, G., Kahle, D., Vogt, T., and Char, S. 1991 Sequence changes in both flanking sequences of a pre-tRNA influence the cleavage specificity of RNase P. J. Mol. Biol. 217:637-648.
231. Krupp, G. 1993 Antisense oligoribonucleotides and RNase P. A great potential. Biochimie 75:135-139.
232. Krzyzaniak, A., Barciszewski, J., Salanski, P., and Jurczak, J. 1994 The Non-Enzymatic Specific Amino-Acylation of Transfer RNA at High Pressure. Int. J. Biol. Macromol. 16:153-158.
233. Kufel, J. and Kirsebom, L.A. 1994 Cleavage site selection by M1 RNA, the catalytic subunit of Escherichia coli RNase P, is influenced by pH. J Mol Biol 244:511-521.
234. Kuhnke, G., Theres, C., Fritz, H.J., and Ehring, R. 1989 RNA polymerase and gal repressor bind simultaneously and with DNA bending to the control region of the Escherichia coli galactose operon. EMBO J. 8:1247-1255.
235. Kulikov, V.A., Shlyapnikov, S.V., and Yakovlev, G.I. 1985 Primary structure of guanyl-specific ribonuclease from Penicillium brevicompactum fungi. Bioorg. Khim. 11:334-345.
236. Kunkel, T.A. 1985 Rapid and efficient site-specific mutagenesis without phenotypic selection. Proc. Natl. Acad. Sci. USA 82:488-492.
237. Laggerbauer, B., Murphy, F.L., and Cech, T.R. 1994 Two major tertiary folding transitions of the Tetrahymena catalytic RNA. EMBO J. 13:2669-2676.
238. LaGrandeur, T.E., Darr, S.C., Haas, E.S., and Pace, N.R. 1993 Characterization of the RNase P RNA of Sulfolobus acidocaldarius. J. Bacteriol. 175:5043-5048.
239. Lagrandeur, T.E., Hüttenhofer, A., Noller, H.F., and Pace, N.R. 1994 Phylogenetic comparative chemical footprint analysis of the interaction between ribonuclease p RNA and tRNA. EMBO J. 13:3945-3952.
240. Lai, C.Y. and Baumann, P. 1992 Genetic analysis of an aphid endosymbiont DNA fragment homologous to the rnpA-rpmH-dnaA-dnaN-gyrB region of eubacteria. Gene 113:175-181.
241. Lamond, A.I. 1988 RNA editing and the mysterious undercover genes of trypanosomatid mitochondria. Trends in Biochem. Sci. 13:283-284.
242. Lassocinski, W. 1982 Substrate Specificity of Ribonucleases of Phosphate-Supplied and Phosphate-Deficient Spirodela. Biochem. Physiol. Pflanz. Bpp. 177:125-136.
243. Lawrence, N.P. and Altman, S. 1986 Site directed Mutagenesis of MI RNA, The RNA subunit of Escherichia coli ribonuclease P. J. Mol. Biol. 191:163-175.
244. Lawrence, N., Wesolowski, D., Gold, H., Bartkiewicz, M., Guerrier-Takada, C., McClain, W.H., and Altman, S. 1987 Characteristics of ribonuclease P from various organisms. Cold Spring. Harb. Symp. Quant. Biol.
245. Lawrence, N.P., Richman, A., Amini, R., and Altman, S. 1987 Heterologous enzyme function in Escherichia coli and the selection of genes encoding the catalytic RNA subunit of RNase P. Proc. Natl. Acad. Sci. USA 84:6825-6829.
246. Lawrence, N.P., Richman, A., Amini, R., and Altman, S. 1987 Selection and characterization of the gene for the catalytic RNA subunit of RNase P from several Enterobacteriaceae. Proc. Natl. Avad. Sci. USA 84:6825-6829.
247. Lawrence, N., Wesoloski, D., Gold, H., Bartkiewicz, M., C., G.-T., McClain, W.H., and Altman, S. 1987 Characteristics of Ribonuclease P from various organisms. Cold Springs Harbor Symposia on Quantitative Biology 52:233-238.
248. Le, S.Y. and Zuker, M. 1991 Predicting common foldings of homologous RNAs. J. Biomol. Struct. Dyn. 8:1027-1044.
249. Lee, J.Y. and Engelke, D.R. 1989 Partial characterization of an RNA component that copurifies with Saccharomyces cerevisiae RNase P. Mol. Cell. Biol. 9:2536-2543.
250. Lee, Y., Ramamoorthy, R., Park, C.U., and Schmidt, F.J. 1989 Sites of initiation and pausing in the Escherichia coli rnpB (M1 RNA) transcript. J. Biol. Chem. 264:5098-5103.
251. Lee, J.Y., Evans, C.F., and Engelke, D.R. 1991 Expression of RNase P RNA in Saccharomyces cerevisiae is controlled by an unusual RNA polymerase III promoter. Proc. Natl. Acad. Sci. USA 88:6986-6990.
252. Lee, J.Y., Rohlman, C.E., Molony, L.A., and Engelke, D.R. 1991 Characterization of RPR1, an essential gene encoding the RNA component of Saccharomyces cerevisiae nuclear RNase P. Mol. Cell Biol. 11:721-730.
253. Leontis, N., DaLio, A., Strobel, M., and Engelke, D. 1988 Effects of tRNA-intron structure on cleavage of precursor tRNAs by RNase P from Saccharomyces cerevisiae. Nucleic Acids Res. 16:2537-2552.
254. Li, Y., Guerrier, T.C., and Altman, S. 1992 Targeted cleavage of mRNA in vitro by RNase P from Escherichia coli. Proc. Natl. Acad. Sci. USA 89:3185-3189.
255. Lieber, A. and Strauss, M. 1995 Selection of efficient cleavage sites in target RNAs by using a ribozyme expression library. Mol. Cell Biol. 15:540-551.
256. Limauro, S., Benseler, F., and Mclaughlin, L.W. 1994 1-Methylguanosine substitutions of the conserved guanosine residues inactivate the hammerhead ribozyme. Bioorg. Medicinal Chem. Letter 4:2189-2192.
257. Lipson, S.E., Cimino, G.D., and Hearst, J.E. 1988 Structure of M1 RNA as determined by psoralen cross-linking. Biochemistry 27:570-575.
258. Lipson, S.E. and Hearst, J.E. 1989 Dimers of M1 RNA as Determined by Psoralen Crosslinking. Molecular Biology of RNA 33-47.
259. Lisacek, F., Diaz, Y., and Michel, F. 1994 Automatic identification of group I intron cores in genomic DNA sequences. J. Mol. Biol. 235:1206-1217.
260. Liu, M.H., Yuan, Y., and Reddy, R. 1994 Human RNaseP RNA and nucleolar 7-2 RNA share conserved 'To' antigen- binding domains. Mol Cell Biochem 130:75-82.
261. Liu, Y. and Leibowitz, M.J. 1994 Bidirectional effectors of a group I intron ribozyme from Pneumocystis carinii. J. Eukaryot. Microbiol. 41:
262. Liu, F. and Altman, S. 1994 Differential evolution of substrates for an RNA enzyme in the presence and absence of its protein cofactor. Cell 77:1093-1100.
263. Lorsch, J.R. and Szostak, J.W. 1994 In vitro evolution of new ribozymes with polynucleotide kinase activity. Nature 371:31-36.
264. Luger, K., Hommel, U., Herold, M., Hofsteenge, J., and Kirschner, K. 1988 Correct folding of circularly permuted variants of a beta alpha barrel enzyme in vivo. Science 243:206-210.
265. Lumelsky, N. and Altman, S. 1988 Selection and characterization of randomly produced mutants in the gene coding for M1 RNA. J. Mol. Biol. 202:443-454.
266. Lygerou, Z., Mitchell, P., Petfalski, E., Seraphin, B., and Tollervey, D. 1994 The POP1 gene encodes protein component common to the RNase MRP and RNase p ribonucleoproteins. Genes. Dev. 8:1423-1433.
267. Mack, D., Mcleod, R., and Stark, B. 1994 Characterization of ribonuclease P from Toxoplasma gondii. J. Eukaryot. Microbiol. 41:
268. Major, F., Turcotte, M., Gautheret, D., Lapalme, G., Fillion, E., and Cedergren, R. 1991 The combination of symbolic and numerical computation for three- dimensional modeling of RNA. Science 253:1255-1260.
269. Major, F., Gautheret, D., and Cedergren, R. 1993 Reproducing the three-dimensional structure of a tRNA molecule from structural constraints. Proc. Natl. Acad. Sci. U A 90:9408-9412.
270. Malhotra, A., Tan, R., and Harvey, S.C. 1994 Modeling large RNAs and ribonucleoprotein particles using molecular mechanics techniques. Biophys. J. 66:1777-1795.
271. Mamula, M.J., Baer, M., Craft, J., and Altman, S. 1989 An immunological determinant of RNase P protein is conserved between Escherichia coli and humans. Proc. Natl. Acad. Sci. USA 86:8717-8721.
272. Manam, S. and C., V.T.G. 1987 Separation and characterization of 5' and 3' tRNA processing nucleases from rat liver mitochondria. J. Biol. Chem. 262:10272-10279.
273. Mande, S.C., Raghunathan, S., Salunke, D.M., Islam, K.M., Swamy, M.J., Surolia, A., and Vijayan, M. 1988 Structural studies on peanut lectin. Indian J. Biochem. Biophys. 25:1-2.
274. Mans, R.M., Guerrier, T.C., Altman, S., and Pleij, C.W. 1990 Interaction of RNase P from Escherichia coli with pseudoknotted structures in viral RNAs. Nucleic Acids Res. 18:3479-3487.
275. Marchfelder, A. and Brennicke, A. 1993 Plant mitochondrial RNase P and E. coli RNase P have different substrate specificities. Biochem. Mol. Biol. Int. 29:621-633.
276. Marchfelder, A. and Brennicke, A. 1994 Characterization and partial purification of tRNA processing activities from potato mitochondria. Plant. Physiol. 105:1247-1254.
277. Marsh, T.L. and Pace, N.R. 1985 Ribonuclease P catalysis differs from ribosomal RNA self-splicing. Science 229:79-80.
278. Mattsson, J.G., Svard, S.G., and Kirsebom, L.A. 1994 Characterization of the Borrelia burgdorferi RNase P RNA gene reveals a novel tertiary interaction. J. Mol. Biol. 241:1-6.
279. McClain, W.H., Guerrier-Takada, C., and Altman, S. 1987 Model substrates for an RNA enzyme. Science 238:527-530.
280. McClain, W.H., Foss, K., Schneider, J., Guerrier-Takada, C., and Altman, S. 1987 Suppressor and novel mutants of bacteriophage T4 tRNA(Gly). J. Mol. Biol. 193:223-226.
281. McCorkle, G.M. and Altman, S. 1987 RNA's as catalysts. J. Chem. Ed. 64:221-226.
282. Michel, F. and Westhof, E. 1990 Modelling of the three-dimensional architecture of group I catalytic introns based on comparative sequence analysis. J. Mol. Biol. 216:585-610.
283. Miczak, A., Ford, J., Marian, M., and Apirion, D. 1983 RNA processing: New mutants that affect endonucleolytic processing of RNA. Biochem. Biophys. Res. Commun. 114:690-698.
284. Miczak, A., Srivastava, R.A., and Apirion, D. 1991 Location of the RNA-processing enzymes RNase III, RNase E and RNase P in the Escherichia coli cell. Mol. Microbiol. 5:1801-1810.
285. Miller, D. and Martin, N.C. 1983 Characterization of the Yeast mitochondrial locus necessary for tRNA biosynthesis: DNA sequence analysis and identification of a new transcript. Cell 34:911-917.
286. Milligan, J.F. and Uhlenbeck, O.C. 1989 Synthesis of small RNAs using T7 RNA polymerase. Methods Enzymol. 164:51-62.
287. Milligan, J.F. and Uhlenbeck, O.C. 1989 Determination of RNA-protein contacts using thiophosphate substitutions. Biochemistry 28:2849-2855.
288. Min, W., Dunn, A.J., and Jones, D.H. 1992 Nonglycosylated Recombinant Pro-Concanavalin-A Is ActiveWithout Polypeptide Cleavage. EMBO J. 11:1303-1307.
289. Mitchelson, K. and Stephen, J. 1991 Processing of histidine transfer RNA precursors in tobacco chloroplasts. Nucleic Acids Res. 19:3150.
290. Moazed, D. and Noller, H.F. 1989 Interaction of tRNA with 23S rRNA in the Ribosomal A, P, and E Sites. Cell 57:585-597.
291. Moazed, D. and Noller, H.F. 1991 Sites of interaction of the CCA end of peptidyl-tRNA with 23S rRNA. Proc. Natl. Acad. Sci. USA 88:3725-3728.
292. Moore, M.J. and Sharp, P.A. 1992 Site-specific modification of pre-mRNA: the 2'hydroxyl groups at the splice sites. Science 256:992-997.
293. Morales, M.J., Wise, C.A., Hollingsworth, M.J., and Martin, N.C. 1989 Characterization of yeast mitochondrial RNase P: An intact RNA subunit is not essential for activity. Nucleic Acids Res. 17:6865-6882.
294. Morales, M.J., Dang, Y.L., Lou, Y.C., Sulo, P., and Martin, N.C. 1992 A 105-kDa protein is required for yeast mitochondrial RNase P activity. Proc Natl Acad Sci U. S. A. 89:9875-9879.
295. Morse, D.P. and Schmidt, F.J. 1992 Sequences encoding the protein and RNA components of ribonuclease P from Streptomyces bikiniensis var. zorbonensis. Gene 117:61-66.
296. Morse, D.P. and Schmidt, F.J. 1993 Suppression of loss-of-function mutations in Escherichia coli ribonuclease P RNA (M1 RNA) by a specific base-pair disruption. J. Mol. Biol. 230:11-14.
297. Motamedi, H., Lee, K., Nichols, L., and Schmidt, F.J. 1982 An RNA species involved in Escherichia coli ribonuclease P activity. Gene cloning and effect on transfer RNA synthesis in vivo. J. Mol. Biol. 162:535-550.
298. Motamedi, H., Lee, Y., and Schmidt, F.J. 1984 Tandem promoters preceding the gene for the M1 RNA component of E. coli ribonuclease P. Proc. Natl. Acad. Sci. USA 81:3959-3963.
299. Mujeeb, A., Bishop, K., Peterlin, B.M., Turck, C., Parslow, T.G., and James, T.L. 1994 NMR structure of a biologically active peptide containing the RNA-binding domain of human immunodeficiency virus type 1 tat. Proc. Natl. Acad. Sci. USA 91:8248-8252.
300. Muller, G., Gaspin, C., Etienne, A., and Westhof, E. 1993 Automatic display of RNA secondary structures. Comput. Appl. Biosci. 9:551-561.
301. Mullis, K.B. and Faloona, F.A. 1987 Specific synthesis of DNA in vitro via a polymerase-catalyzed chain reaction. Methods Enzymol.
302. Murphy, F.L., Wang, Y.H., Griffith, J.D., and Cech, T.R. 1994 Coaxially stacked RNA helices in the catalytic center of the tetrahymena ribozyme. Science 265:1709-1712.
303. Musier-Forsyth, K. and Schimmel, P. 1994 Acceptor helix interactions in a class II tRNA synthetase: photoaffinity cross-linking of an RNA miniduplex substrate. Biochemistry 33:773-779.
304. Nesbitt, S. and Goodchild, J. 1994 Further studies on the use of oligonucleotide facilitators to increase ribozyme turnover. Antisense Res. Dev. 4:243-249.
305. Ng, M., Benseler, F., Tuschl, T., and Eckstein, F. 1994 Isoguanosine substitution of conserved adenosines in the hammerhead ribozyme. Biochemistry 33:12119-12126.
306. Nichols, L. and Schmidt, F.J. 1988 Dependence of M1 RNA substrate specificity on magnesium ion concentration. Nucleic Acids Res. 16:2931-2942.
307. Nichols, M., Söll, D., and Willis, I. 1988 Yeast RNase P: catalytic activity and substrate binding are separate functions. Proc. Natl. Acad. Sci. USA 85:1379-1383.
308. Nieuwlandt, D.T., Haas, E.S., and Daniels, C.J. 1991 The RNA component of RNase P from the archaebacterium Haloferax volcanii. J. Biol. Chem. 266:5689-5695.
309. Nilsson, G., Lundberg, U., and von, G.A. 1988 In vivo and in vitro identity of site specific cleavages in the 5' non-coding region of ompA and bla mRNA in Escherichia coli. EMBO J. 7:2269-2275.
310. Nilsson, P. and Uhlin, B.E. 1991 Differential decay of a polycistronic Escherichia coli transcript is initiated by RNaseE-dependent endonucleolytic processing. Mol. Microbiol. 5:1791-1799.
311. Nishimura, S., Chromatographic mobilities of modified nucleotides, in Transfer RNA: Structure, Properties and Recognition, D.S.a.J.N.A. P.R. Schimmel, Editor. 1979, Cold Spring Harbor Press: Cold Spring Harbor, N.Y. p. 551-552.
312. Nolan, J.M., Burke, D.H., and Pace, N.R. 1993 Circularly permuted tRNAs as specific photoaffinity probes of ribonuclease P RNA structure. Science 261:762-765.
313. Noller, H.F., W. Hoffarth and L. Zimiak. 1992 Unusual resistance of peptidyl transferase to protein extraction procedures. Science 256:1416-1419.
314. Nomura, T. and Ishihama, A. 1988 A novel function of RNase P from Escherichia coli: processing of a suppressor tRNA precursor. EMBO J. 7:3539-3545.
315. Ogasawara, N., Moriya, S., K., v.M., Hansen, F.G., and Yoshikawa, H. 1985 Conservation of genes and their organization in the chromosomal replication origin region of Bacillus subtilis and Escherichia coli. EMBO J. 4:3345-3350.
316. Oh, B.-K. and Pace, N.R. 1994 Interaction of the 3'-end of tRNA with ribonuclease P RNA. Nucleic Acids Res. 22:4087-4094.
317. Ohnishi, K. 1990 Possible evolutionary origin of primitive protein-encoding mRNAs as a virusoid-like ribo-organism. Nucleic Acids Symp. Ser. 1990:39-40.
318. Ohnishi, K. 1991 Origin of virusoids and M1 RNA: their evolutionary relationship to the E.coli rrnD operon. Nucleic Acids Symp. Ser. 1991:123-124.
319. Orellana, O., Cooley, L., and Söll, D. 1986 The additional guanylate at the 5' terminus of Escherichia coli tRNA super(His) is the result of unusual processing by RNase P. Mol. Cell. Biol. 6:525-529.
320. Orgel, L.E. 1986 RNA catalysis and the origins of life. J. Theor. Biol. 123:127-149.
321. Pace, N.R. and Marsh, T.L. 1985 RNA catalysis and the origin of life. Orig. Life 16:97-116.
322. Pace, N.R., Reich, C., James, B.D., Olsen, G.J., Pace, B., and Waugh, D.S. 1987 Structure and catalytic function in ribonuclease P. Cold Spring Harb. Symp. Quant Biol 52:239-248.
323. Pace, N.R., Smith, D.K., Olsen, G.J., and James, B.D. 1989 Phylogenetic comparative analysis and the secondary structure of ribonuclease P RNA - a review. Gene 82:65-75.
324. Pace, N.R. and Smith, D. 1990 Ribonuclease P: function and variation. J. Biol. Chem. 265:3587-3590.
325. Pace, N.R. and Waugh, D.S. 1991 Design of simplified ribonuclease P RNA by phylogenetic comparison. Methods Enzymol.
326. Pace, U., Bockman, J.M., Mackay, B.J., Miller, W.H., Dmitrovsky, E., and Goldberg, A.R. 1994 A ribozyme which discriminates in vitro between PML/RAR alpha, the t(15;17)-associated fusion RNA of acute promyelocytic leukemia, and PML and RAR alpha, the transcripts from the nonrearranged alleles. Cancer Res 54:6365-6369.
327. Padgett, R.A., Podar, M., Boulanger, S.C., and Perlman, P.S. 1994 The stereochemical course of group II intron self-splicing. Science 266:1685-1688.
328. Pagan-Ramos, E., Tranguch, A.J., Kindelberger, D.W., and Engelke, D.R. 1994 Replacement of the Saccharomyces cerevisiae RPR1 gene with heterologous RNase P RNA genes. Nucleic Acids Res. 22:200-207.
329. Paisley, T.E. and Vantuyle, G.C. 1994 The processing of wild type and mutant forms of rat nuclear pre-tRNA(Lys) by the homologous RNase p. Nucleic Acids Res 22:3347-3353.
330. Palmer, J.R., Nieuwlandt, D.T., and Daniels, C.J. 1994 Expression of a yeast intron-containing tRNA in the archaeon haloferax volcanii. J. Bacteriol. 176:3820-3823.
331. Pan, T., Gutell, R.R., and Uhlenbeck, O.C. 1991 Folding of circularly permuted transfer RNAs. Science 254:1361-1364.
332. Pan, T. and Zhong, K. 1994 Selection of circularly permuted ribozymes from Bacillus subtilis RNAse P by substrate binding. Biochemistry 33:14207-14212.
333. Pan, T. 1995 Higher order folding and domain analysis of the ribozyme from Bacillus subtilis Ribonuclease P. Biochemistry 34:902-909.
334. Panagiotidis, C.A., Drainas, D., and Huang, S.C. 1992 Modulation of ribonuclease P expression in Escherichia coli by polyamines. Int. J. Biochem. 24:1625-1631.
335. Pascual, A. and Vioque, A. 1994 Sequence and structure of the RNA subunit of RNase P from the Cyanobacterium pseudoanabaena sp. PCC6903. Bba. Gene Struct. Express. 1218:463-465.
336. Peck-Miller, K.A. and Altman, S. 1991 Kinetics of the processing of the precursor to 4.5 S RNA, a naturally occurring substrate for RNase P from Escherichia coli. J Mol. Biol 221:1-5.
337. Perez, M.J., del, S.G., Lurz, R., de, l.C.G., Dobrinski, B., and Espinosa, M. 1989 Induced bending of plasmid pLS1 DNA by the plasmid-encoded protein RepA. J. Biol. Chem. 264:21334-339.
338. Perreault, J.P. and Altman, S. 1992 Important 2'-hydroxyl Groups in Model Substrates for M1 RNA, the Catalytic RNA Subunit of RNase-P from Escherichia coli. J Mol. Biol 226:399-409.
339. Perreault, J.P. and Altman, S. 1993 Pathway of activation by magnesium ions of substrates for the catalytic subunit of RNase P from Escherichia coli. J. Mol. Biol. 230:750-756.
340. Piper, P.W. and Straaby, K.B. 1989 Processing of transcripts of a dimeric tRNA gene in yeast uses the nuclease responsible for maturation of the 3' termini upon 5 S and 37 S precursor rRNAs. FEBS Lett. 250:311-316.
341. Plautz, G. and Apirion, D. 1981 Processing of RNA in Escherichia coli is limited in the absence of ribonuclease III, ribonuclease E and ribonuclease P. J. Mol. Biol. 149:813-819.
342. Pley, H.W., Flaherty, K.M., and McKay, D.B. 1994 Three-dimensional structure of a hammerhead ribozyme. Nature 372:68-74.
343. Pley, H.W., Flaherty, K.M., and McKay, D.B. 1994 Model for an RNA tertiary interaction from the structure of an intermolecular complex between a GAAA tetraloop and an RNA helix. Nature 372:111-113.
344. Plohl, M., Borstnik, B., Ugarkovic, D., and Gamulin, V. 1990 Sequence-induced curvature of Tenebrio molitor satellite DNA. Biochimie 72:665-670.
345. Podyminogin, M.A., Vlassov, V.V., and Giege, R. 1993 Synthetic RNA-Cleaving Molecules Mimicking Ribonuclease a Active Center - Design and Cleavage of tRNA Transcripts. Nucleic Acids Res. 21:5950-5956.
346. Potashkin, J. and Frendewey, D. 1990 A mutation in a single gene of Schizosaccharomyces pombe affects the expression of several snRNAs and causes defects in RNA processing. EMBO J. 9:525-534.
347. Predki, P.F., Nayak, L.M., Gottlieb, M., and Regan, L. 1995 Dissecting RNA-protein interactions: RNA-RNA recognition by rop. Cell 80:41-50.
348. Puglisi, E.V., Puglisi, J.D., Williamson, J.R., and Rajbhandary, U.L. 1994 NMR analysis of tRNA acceptor stem microhelices: discriminator base change affects tRNA conformation at the 3' end. Proc. Natl. Acad. Sci. USA 91:11467-11471.
349. Pyle, A.M., Moran, S., Strobel, S.A., Chapman, T., Turner, D.H., and Cech, T.R. 1994 Replacement of the conserved G•U with a G-C pair at the cleavage site of the tetrahymena ribozyme decreases binding, reactivity, and fidelity. Biochemistry 33:13856-13863.
350. Quigley, G.J. and Rich, A. 1976 Science 194:976.
351. Quigley, G.J., Teeter, M.M., and Rich, A. 1978 Structural analysis of spermine and magnesium ion binding to yeast phenylalanine transfer RNA. Proc. Natl. Acad. Sci. USA 75:64-68.
352. Ragnini, A., Grisanti, P., Rinaldi, T., Frontali, L., and Palleschi, C. 1991 Mitochondrial genome of Saccharomyces douglasii: genes coding for components of the protein synthetic apparatus. Curr. Genet. 19:169-174.
353. Ramamoorthy, R. and Schmidt, F.J. 1991 Transcript hairpin structures are not required for RNA polymerase pausing in the gene encoding the E. coli RNase P RNA, M1 RNA. FEBS Lett. 295:227-229.
354. Ray, B.K. and Apirion, D. 1981 RNAase P is dependent on RNAase E action in processing monomeric RNA precursors that accumulate in an RNAase E- mutant of Escherichia coli. J. Mol. Biol. 149:599-617.
355. Ray, B.K., Singh, B., Roy, M.K., and Apirion, D. 1982 Ribonuclease E is Involved in the Processing of 5-S rRNA From a Number of rRNA Transcription Units. Eur. J. Biochem. 125:283-289.
356. Reed, R.E., Baer, M.F., Guerrier-Takada, C., Donis-Keller, H., and Altman, S. 1982 Nucleotide sequence of the gene encoding the RNA subunit (M1 RNA) of ribonuclease P from Escherichia coli. Cell 30:627-636.
357. Reed, R.E. and Altman, S. 1983 Repeated sequences and open reading frames in the 3' flanking region of the gene for the RNA subunit of Escherichia coli ribonuclease P. Proc. Natl. Acad. Sci. USA 80:5359-5363.
358. Reich, C., Gardiner, K.J., Olsen, G.J., Pace, B., Marsh, T.L., and Pace, N.R. 1986 The RNA component of the Bacillus subtilis RNase P: sequence, activity, and partial secondary structure. J. Biol. Chem. 261:7888-7893.
359. Reich, C., Olsen, G.J., Pace, B., and Pace, N.R. 1988 Role of the protein moiety of ribonuclease P, a ribonucleoprotein enzyme. Science 239:178-181.
360. Reich, C.I. 1988 La Ribonuclease P de Bacillus. Ph. D. Thesis, University of Buenos Aires
361. Reilly, R.M. and RajBhandary, U.L. 1986 A single mutation in loop IV of Escherichia coli SuIII tRNA blocks processing at both 5'- and 3'- ends of the precursor tRNA. J. Biol. Chem. 247:2928-2935.
362. Rich, A. and RajBhandary, U.L. 1976 Transfer RNA: molecular structure, sequence, and properties. Annu. Rev. Biochem. 805-860.
363. Richardson, P.L., Gross, M.L., Lightwahl, K.J., Smith, R.D., and Schepartz, A. 1994 A uniquely modified RNA: introduction of a single RNA cleavage agent into the M1 ribozyme. Bioorg. Medicinal Chem. Letter 4:2133-2138.
364. Rivera, M.C., and J. A. Lake. 1992 Evidence that eukaryotes and eocyte prokaryotes are immediate relatives. Science 257:74-76.
365. Robertson, H.D., Altman, S., and Smith, J.D. 1972 Purification and properties of a specific Escherichia coli ribonuclease which cleaves a tyrosine transfer ribonucleic acid precursor. J. Biol. Chem. 247:5243-5251.
366. Roselli, D.M. and Marsh, T.L. 1990 Purification and characterization of RNase P from Clostridium sporogenes. Mol. Microbiol. 4:1393-400.
367. Rossi, J.J. and Sarver, N. 1990 RNA enzymes (ribozymes) as antiviral therapeutic agents. Trends in Biotech. 8:179-183.
368. Saiki, R.K., Gelfand, D.H., Stoffel, S., Scharf, S.J., Higuchi, R., Horn, G.T., Mullis, K.B., and Erlich, H.A. 1988 Primer-directed enzymatic amplification of DNA with a thermostable DNA polymerase. Science 239:487-491.
369. Sakamoto, H., Kimura, N., Nagawa, F., and Shimura, Y. 1983 Nucleotide sequence and stability of the RNA component of RNase P from a temperature-sensitive mutant of E. coli. Nucleic Acids Res. 11:8237-8251.
370. Sakamoto, H., Kimura, N., and Shimura, Y. 1983 Processing of transcription products of the gene encoding the RNA component of RNase P. Proc. Natl. Acad. Sci. USA 80:6187-6191.
371. Sambrook, J., E. F. Fritsch, and T. Maniatis, Molecular cloning: a laboratory manual, 2nd ed. 1989, Cold Spring Harbor, N.Y.: Cold Spring Harbor Laboratory.
372. Sampson, J.R. and Uhlenbeck, O.C. 1988 Biochemical and physical characterization of an unmodified yeast phenylalanine transfer RNA transcribed in vitro. Proc. Natl. Acad. Sci. USA 85:1033-1037.
373. Sampson, J.R., DiRenzo, A.B., Behlen, L.S., and Uhlenbeck, O.C. 1990 Role of the tertiary nucleotides in the interaction of yeast phenylalanine tRNA with its cognate synthetase. Biochemistry 29:2523-2532.
374. Samuelsson, T., Boren, T., Johansen, T.I., and Lustig, F. 1988 Properties of a transfer RNA lacking modified nucleosides. J. Biol. Chem. 263:13692-699.
375. Sanger, F., S. Nicklen, and A. R. Coulson. 1977 DNA sequencing with chain-terminating inhibitors. Proc. Natl. Acad. Sci. USA 74:5463-5467.
376. SantaLucia, J.J., Kierzek, R., and Turner, D.H. 1991 Stabilities of consecutive A.C, C.C, G.G, U.C, and U.U mismatches in RNA internal loops: Evidence for stable hydrogen-bonded U.U and C.C.+ pairs. Biochemistry 30:8242-8251.
377. SantaLucia, J.J., Kierzek, R., and Turner, D.H. 1992 Context dependence of hydrogen bond free energy revealed by substitutions in an RNA hairpin. Science 256:217-219.
378. SantaLucia, J.J. and Turner, D.H. 1993 Structure of (rGGCGAGCC)2 in solution from NMR and restrained molecular dynamics. Biochemistry 32:12612-12623.
379. Schatz, D., Leberman, R., and Eckstein, F. 1991 Interaction of Escherichia coli tRNA(Ser) with its cognate aminoacyl- tRNA synthetase as determined by footprinting with phosphorothioate- containing tRNA transcripts. Proc. Natl. Acad. Sci. USA 88:6132-6136.
380. Schlegl, J., Furste, J.P., Bald, R., Erdmann, V.A., and Hartmann, R.K. 1992 Cleavage efficiencies of model substrates for ribonuclease P from Escherichia coli and Thermus thermophilus. Nucleic Acids Res. 20:5963-5970.
381. Schlegl, J., Hardt, W.D., Erdmann, V.A., and Hartmann, R.K. 1994 Contribution of structural elements to Thermus thermophilus ribonuclease P RNA function. EMBO J. 13:4863-4869.
382. Schmitt, M.E., Bennett, J.L., Dairaghi, D.J., and Clayton, D.A. 1993 Secondary structure of RNase MRP RNA as predicted by phylogenetic comparison. FASEB J. 7:208-213.
383. Segal, I.H., Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems. 1975, New York, N.Y.: John Wiley & Sons. 957.
384. Serra, M.J., Lyttle, M.H., Axenson, T.J., Schadt, C.A., and Turner, D.H. 1993 RNA hairpin loop stability depends on closing base pair. Nucleic Acids Res. 21:3845-3849.
385. Shah, K., Wu, H.Y., and Rana, T.M. 1994 Synthesis of uridine phosphoramidite analogs: reagents for site-specific incorporation of photoreactive sites into RNA sequences. Bioconjugate Chemistry 5:508-512.
386. Shimayama, T. 1994 Effects of deoxyribonucleotide substitutions in the substrate strand on hammerhead ribozyme-catalyzed reactions. Gene 149:41-46.
387. Shimura, Y. and Shiraishi, H. 1990 Genetics of transfer RNA processing in Escherichia coli. Methods Enzymol.
388. Shiraishi, H. and Shimura, Y. 1986 Mutations affecting two distinct functions of the RNA component of RNase P. EMBO J. 5:3673-3679.
389. Shiraishi, H. and Shimura, Y. 1988 Functional domains of the RNA component of ribonuclease P revealed by chemical probing of mutant RNAs. EMBO J. 7:3817-3821.
390. Shiraishi, H. and Shimura, Y. 1988 A rapid and efficient method for targeted random mutagenesis. Gene 64:313-319.
391. Shlyapnikov, M.G., Ksenzenko, V.N., Kryukov, V.M., and Bayev, A.A. 1986 Nucleotide sequence of the bacteriophage T5 DNA fragment which contains the gene for tRNA super(Asp). Eur. J. Biochem. 156:285-289.
392. Shu, H.H. and Martin, N.C. 1991 RNase P RNA in Candida glabrata mitochondria is transcribed with substrate tRNAs. Nucleic Acids Res. 19:6221-6226.
393. Shu, H.H., Wise, C.A., Clark-Walker, G.D., and Martin, N.C. 1991 A gene required for RNase P activity in Candida (Torulopsis) glabrata mitochondria codes for a 227-nucleotide RNA with homology to bacterial RNase P RNA. Mol. Cell Biol. 11:1662-1667.
394. Shumyatsky, G. and Reddy, R. 1992 Compilation of small RNA sequences. Nucleic Acids Res.
395. Sioud, M. 1994 Interaction between tumour necrosis factor alpha ribozyme and cellular proteins - involvement in ribozyme stability and activity. J Mol Biol 242:619-629.
396. Skovgaard, O. 1990 Nucleotide sequence of a Proteus mirabilis DNA fragment homologous to the 60K-rnpA-rpmH-dnaA-dnaN-recF-gyrB region of Escherichia coli. Gene 93:27-34.
397. Smith, D., Burgin, A.B., Haas, E.S., and Pace, N.R. 1992 Influence of metal ions on the ribonuclease P reaction. Distinguishing substrate binding from catalysis. J Biol. Chem. 267:2429-2436.
398. Smith, D. and Pace, N.R. 1993 Multiple magnesium ions in the ribonuclease P reaction mechanism. Biochemistry 32:5273-5281.
399. Srivastava, R.A., Srivastava, N., and Apirion, D. 1991 RNA processing enzymes RNase III, E and P in Escherichia coli are not ribosomal enzymes. Biochem. Int. 25:57-65.
400. Srivastava, R.A., Srivastava, N., and Apirion, D. 1992 Characterization of the RNA processing enzyme RNase III from wild type and overexpressing Escherichia coli cells in processing natural RNA substrates. Int. J. Biochem. 24:737-749.
401. Stahl, D.A., Meyhack, B., and Pace, N.R. 1980 Recognition of local nucleotide conformation in contrast to sequence by a rRNA processing endonuclease. Proc. Natl. Acad. Sci. USA 77:5644-5648.
402. Stark, B.C., Kole, R., Bowman, E.J., and Altman, S. 1978 Ribonuclease P: An Enzyme with an Essential RNA Component. Proc. Natl. Acad. Sci. USA 75:3717- 3721.
403. Steinecke, P., Steger, G., and Schreier, P.H. 1994 A stable hammerhead structure is not required for endonucleolytic activity of a ribozyme in vivo. Gene 149:47-54.
404. Steiner, V.K. 1989 RNA-molecules as biologic catalysts. Biol. Rundsch. 27:65-72.
405. Steitz, T.A. and Steitz, J.A. 1993 A general two-metal-ion mechanism for catalytic RNA. Proc. Natl. Acad. Sci. USA 90:6498-502.
406. Stern, S., Moazed, D., and Noller, H.F. 1988 Structural analysis of RNA using chemical and enzymatic probing monitored by primer extension. Methods Enzymol. 164:481-491.
407. Strobel, S.A. and Cech, T.R. 1995 Minor groove recognition of the conserved G•U pair at the Tetrahymena ribozyme reaction site. Science 267:675-679.
408. Subbarao, M.N., Makam, H., and Apririon, D. 1984 A site in a tRNA precursor that can be processed by the whole RNase P enzyme but not by the RNA alone. J. Biol. Chem. 259:14339-14342.
409. Sugimoto, N., Katoh, M., Nakano, S., Ohmichi, T., and Sasaki, M. 1994 RNA/DNA hybrid duplexes with identical nearest-neighbor base-pairs have identical stability. Febs Lett 354:74-78.
410. Sullenger, B.A. and Cech, T.R. 1994 Ribozyme-mediated repair of defective mRNA by targeted trans-splicing. Nature 371:619-622.
411. Sulo, P., Groom, K.R., Wise, C., Steffen, M., and Martin, N. 1995 Successful transformation of yeast mitochondria with RPM1: an approach for in vivo studies of mitochondrial RNase P RNA structure, function and biosynthesis. Nucleic Acids Research 23:856-860.
412. Sun, L.Q., Warrilow, D., Wang, L., Witherington, C., Macpherson, J., and Symonds, G. 1994 Ribozyme-mediated suppression of moloney murine leukemia virus and human immunodeficiency virus type i replication in permissive cell lines. Proc. Natl. Acad. Sci. USA 91:9715-9719.
413. Surratt, C.K., Carter, B.J., and Hecht, S.M. 1989 Processing of a Synthetic tRNA Precursor Model by E. coli RNase P and M1 RNA. Molecular Biology of RNA 79-88.
414. Surratt, C.K., Carter, B.J., Payne, R.C., and Hecht, S.M. 1990 Metal ion and substrate structure dependence of the processing of tRNA precursors by RNase P and M1 RNA. J. Biol. Chem. 265:22513-22519.
415. Surratt, C.K., Lesnikowski, Z., Schifman, A.L., Schmidt, F.J., and Hecht, S.M. 1990 Construction and processing of transfer RNA precursor models. J. Biol. Chem. 265:22506-22512.
416. Svard, S.G. and Kirsebom, L.A. 1992 Several regions of a tRNA precursor determine the Escherichia coli RNase P cleavage site. J. Mol. Biol. 227:1019-1031.
417. Svard, S.G. and Kirsebom, L.A. 1993 Determinants of Escherichia coli RNase P cleavage site selection: a detailed in vitro and in vivo analysis. Nucleic Acids Res. 21:427-434.
418. Svard, S.G., Mattsson, J.G., Johansson, K.E., and Kirsebom, L.A. 1994 Cloning and characterization of the RNase P RNA genes from two porcine mycoplasmas. Mol. Microbiol. 11:849-859.
419. Symons, R.H. 1994 Ribozymes. Curr. Opin. Struct. Biol. 4:322-330.
420. Szostak, J.W. and Ellington, A.D., In Vitro selection of functional RNA sequences, in The RNA World, R.F.G.a.J.F. Atkins, Editor. 1993, Cold Spring Harbor Laboratory Press: Cold Spring Harbor, N.Y. p. 511-534.
421. Szymkowiak, C., Reynolds, R.L., Chamberlin, M.J., and Wagner, R. 1988 The tRNAGlu2 gene in the rrnB operon of E. coli is a prerequisite for correct RNase III processing in vitro. Nucleic Acids Res. 16:7885-7899.
422. Tabler, M., Homann, M., Tzortzakaki, S., and Sczakiel, G. 1994 A three-nucleotide helix I is sufficient for full activity of a hammerhead ribozyme: advantages of an asymmetric design. Nucleic Acids Res. 22:3958-3965.
423. Takeshima, T., Inoue, C., Kitagawa, Y., and Kusano, T. 1989 Nucleotide sequence of a Thiobacillus ferrooxidans chromosomal gene, which encodes putative RNA component of RNase P. Nucleic Acids Res. 17:9482.
424. Talbot, S.J. and Altman, S. 1994 Kinetic and thermodynamic analysis of RNA-protein interactions in the RNase P holoenzyme from Escherichia coli. Biochemistry 33:1406-1411.
425. Talbot, S.J. and Altman, S. 1994 Gel retardation analysis of the interaction between C5 protein and M1 RNA in the formation of the ribonuclease P holoenzyme from Escherichia coli. Biochemistry 33:1399-405.
426. Tallsjö, A. and Kirsebom, L.A. 1993 Product release is a Product release is a rate-limiting step during cleavage by the catalytic RNA subunit of Escherichia coli RNase P [published erratum appears in Nucleic Acids Res 1993 Apr 11;21(7):1686]rate-limiting step during cleavage by the catalytic RNA subunit of Escherichia coli RNase P. Nucleic Acids Res. 21:51-57.
427. Tallsjö, A., Svard, S.G., Kufel, J., and Kirsebom, L.A. 1993 A novel tertiary interaction in M1 RNA, the catalytic subunit of Escherichia coli RNase P. Nucleic Acids Res. 21:3927-3933.
428. Tate, S., Ono, A., and Kainosho, M. 1994 An alternative triple-resonance method for the through- bond correlation of intranucleotide H1' and H8 NMR signals of purine nucleotides. Application to a DNA dodecamer with fully C-13/N-15-labeled deoxyadenosine residues. J. Am. Chem. Soc. 116:5977-5978.
429. Thurlow, D.L., Shilowski, D., and Marsh, T.L. 1991 Nucleotides in precursor tRNAs that are required intact for catalysis by RNase P RNAs. Nucleic Acids Res. 19:885-891.
430. Tranguch, A.J. and Engelke, D.R. 1993 Comparative structural analysis of nuclear RNase P RNAs from yeast. J. Biol. Chem. 268:14045-14055.
431. Tranguch, A.J., Kindelberger, D.W., Rohlman, C.E., Lee, J.Y., and Engelke, D.R. 1994 Structure-Sensitive RNA Footprinting of Yeast Nuclear Ribonuclease P. Biochemistry 33:1778-1787.
432. Tuschl, T., Gohlke, C., Jovin, T.M., Westhof, E., and Eckstein, F. 1994 Three-dimensional model for the hammerhead ribozyme based on fluorescence measurements. Science 266:785-789.
433. Uchiyama, Y., Miura, Y., Inoue, H., Ohtsuka, E., Ueno, Y., Ikehara, M., and Iwai, S. 1994 Studies of the interactions between Escherichia coli ribonuclease HI and its substrate. J. Mol. Biol. 243:782-791.
434. Uchiyama, Y., Iwai, S., Ueno, Y., Ikehara, M., and Ohtsuka, E. 1994 Role of the Mg2+ ion in the Escherichia coli ribonuclease HI reaction. J. Biochem. Tokyo 116:1322-1329.
435. Uebayasi, M., Uchimaru, T., Koguma, T., Sawata, S., Shimayama, T., and Taira, K. 1994 Theoretical and experimental considerations on the hammerhead ribozyme reactions: divalent magnesium ion mediated cleavage of phosphorus-oxygen bonds. J. Org. Chem. 59:7414-7420.
436. Usman, N. and Cedergren, R. 1992 Exploiting the Chemical Synthesis of RNA. Trends Biochem. Sci. 17:334-339.
437. Varani, G., Cheong, C., and Tinoco, I.J. 1991 Structure of an unusually stable RNA hairpin. Biochemistry 30:3280-3289.
438. Venkstern, T.V. 1987 [RNA M1 and other catalytically active polyribonucleotides]. Mol. Biol. 21:869-875.
439. Venkstern, T.V. 1988 RNA M1 and other catalytically active polyribonucleotides. Mol. Biol. 21:1.
440. Vioque, A. and Altman, S. 1986 Affinity Chromatography with an immobilized RNA enzyme. Proc. Natl. Acad. Sci. USA 83:5904-5908.
441. Vioque, A., Arnez, J., and Altman, S. 1988 Protein-RNA interactions in the RNase P holoenzyme from Escherichia coli. J. Mol. Biol. 202:835-848.
442. Vioque, A. 1989 Protein synthesis inhibitors and catalytic RNA: effect of puromycin on tRNA precursor processing by the RNA component of Escherichia coli RNase P. FEBS Lett. 246:137-139.
443. Vioque, A. 1992 Analysis of the gene encoding the RNA subunit of ribonuclease P from cyanobacteria. Nucleic Acids Res. 20:6331-6337.
444. Vogelstein, B. and Gillespie, D. 1979 Preparative and analytical purification of DNA from agarose. Proc. Natl. Acad. Sci. USA 76:615-619.
445. Vold, B.S. and Green, C.J. 1988 Processing of a multimeric tRNA precursor from Bacillus subtilis by the RNA component of RNase P. J. Biol. Chem. 263:14390-14396.
446. Wang, M.J., Davis, N.W., and Gegenheimer, P. 1988 Novel mechanisms for maturation of chloroplast transfer RNA precursors. EMBO J. 7:1567-1574.
447. Wang, M.J. and Gegenheimer, P. 1990 Substrate masking: binding of RNA by EGTA-inactivated micrococcal nuclease results in artifactual inhibition of RNA processing reactions. Nucleic Acids Res. 18:6625-6631.
448. Wang, J.F. and Cech, T.R. 1994 Metal ion dependence of active-site structure of the Tetrahymena ribozyme revealed by site-specific photo-cross- linking. J. Am. Chem. Soc. 116:4178-4182.
449. Watanabe, Y., Kawai, G., Yokogawa, T., Hayashi, N., Kumazawa, Y., Ueda, T., Nishikawa, K., Hirao, I., Miura, K., and Watanabe, K. 1994 Higher-order structure of bovine mitochondrial tRNA(Ser)UGA: chemical modification and computer modeling. Nucleic Acids Res. 22:5378-5384.
450. Waugh, D.S. and Pace, N.R. 1986 Catalysis by RNA. Bioessays 4:56-61.
451. Waugh, D.S., Green, C.J., and Pace, N.R. 1989 The design and catalytic properties of a simplified ribonuclease P RNA. Science 244:1569-1570.
452. Waugh, D.S., Sganga, M.W., Raff, M., and Pace, N.R., A site directed mutation in the Bacillus subtilis ribonuclease P RNA that selectively influences its protein dependent reaction, in Mol. Biol. of RNA. 1989, Alan Liss, Inc.: p. 67-77.
453. Waugh, D. 1989 Mutational analysis of catalytic function in Ribonuclease P RNA. Ph.D. Thesis
454. Waugh, D.S. and Pace, N.R. 1990 Complementation of an RNase P RNA (rnpB) gene deletion in Escherichia coli by homologous genes from distantly related eubacteria. J. Bacteriol. 172:6316-6322.
455. Waugh, D.S. and Pace, N.R. 1993 Gap-scan deletion analysis of Bacillus subtilis RNase P RNA. FASEB J. 7:188-195.
456. Weiner, A.M. and Maizels, N. 1987 tRNA-like structures tag the 3' ends of genomic RNA molecules for replication: implications for the origin of protein synthesis. Proc. Natl. Acad. Sci. USA 84:7383-7387.
457. Westhof, E. and Altman, S. 1994 Three-dimensional working model of M1 RNA, the catalytic RNA subunit of ribonuclease P from Escherichia coli. Proc. Natl. Acad. Sci. USA 91:5133-5137.
458. Wilhelm, M.L., Keith, G., Fix, C., and Wilhelm, F.X. 1992 Pleiotropic effect of a point mutation in the yeast SUP4-o tRNA gene: in vivo pre-tRNA processing in S. cerevisiae. Nucleic Acids Res. 20:791-796.
459. Williams, K.P., Imahori, H., Fujimoto, D.N., and Inoue, T. 1994 Selection of novel forms of a functional domain within the Tetrahymena ribozyme. Nucleic Acids Res. 22:2003-2009.
460. Willis, I., Nichols, M., Chisholm, V., Söll, D., Heyer, W.D., Szankasi, P., Amstutz, H., Munz, P., and Kohli, J. 1986 Functional complementation between mutations in a yeast suppressor tRNA gene reveals potential for evolution of tRNA sequences. Proc. Natl. Acad. Sci. USA 83:7860-7864.
461. Willis, I., D., F., Nichols, M., A., H.-W., Schaack, J., and Söll, D. 1986 A single base change in the intron of a serine tRNA affects the rate of RNase P cleavage in vitro and suppressor activity in vivo in Saccharomyces cerevisiae. J. Biol. Chem. 261:5878-5885.
462. Wise, C.A. and Martin, N.C. 1991 Dramatic size variation of yeast mitochondrial RNAs suggests that RNase P RNAs can be quite small. J. Biol. Chem. 266:19154-19157.
463. Wise, C. and Martin, N.C. 1991 Sequence analysis of Saccharomyces exiguus mitochondrial DNA reveals an RNase P RNA gene flanked by two tRNA genes. Nucleic Acids Res. 19:4773.
464. Woese, C.R. 1987 Bacterial evolution. Microbiological Reviews 51:221-271.
465. Woese, C.R., Kandler, O., and M. L. Wheelis. 1990 Towards a natural system of organisms: Proposal for the domains Archaea, Bacteria, and Eucarya. Proc. Natl. Acad. Sci. USA 87:4576-4579.
466. Woese, C.R.a.N.R.P., Probing RNA structure, function, and history by comparative analysis, in The RNA World, R.F.G.a.J.F. Atkins, Editor. 1993, Cold Spring Harbor Laboratory Press: Cold Spring Harbor, NY. p. 91-117.
467. Woisard, A., Fourrey, J.L., and Favre, A. 1994 Multiple folded conformations of a hammerhead ribozyme domain under cleavage conditions. J. Mol. Biol. 239:366-370.
468. Wyatt, J.R., and I. Tinoco, RNA structural elements and RNA function, in The RNA World, R.F.G.a.J.F. Atkins, Editor. 1993, Cold Spring Harbor Laboratory Press: Cold Spring Harbor, NY. p. 465-496.
469. Yamaguchi, S.K., Shinozaki, K., and Sugiura, M. 1987 Processing of precursor tRNAs in a chloroplast lysate. Processing of the 5'-end involves endonucleolytic cleavage by an RNase P-like enzyme and precedes 3'-end maturation. FEBS Lett. 215:132-136.
470. Yeo, A., Kosturka, L.D., and Feiss, M. 1990 Structure of the bacteriophage lambda cohesive end site: Bent DNA on both sides of the site, cosN, at which terminase introduces nicks during chromosome maturation. Virology 174:329-334.
471. Yuan, Y., Tan, E., and Reddy, R. 1991 The 40-kilodalton to autoantigen associates with nucleotides 21 to 64 of human mitochondrial RNA processing/7-2 RNA in vitro. Mol. Cell Biol. 11:5266-5274.
472. Yuan, Y., Hwang, E.S., and Altman, S. 1992 Targeted cleavage of mRNA by human RNase P. Proc Natl Acad Sci U. S. A. 89:8006-8010.
473. Yuan, Y. and Altman, S. 1994 Selection of guide sequences that direct efficient cleavage of mRNA by human ribonuclease P. Science 263:1269-1273.
474. Yue, D.X., Kintanar, A., and Horowitz, J. 1994 Nucleoside modifications stabilize Mg2+ binding in escherichia coli tRNA(Val): an imino proton NMR investigation. Biochemistry 33:8905-8911.
475. Yuyama, N., Ohkawa, J., Koguma, T., Shirai, M., and Taira, K. 1994 A multifunctional expression vector for an anti-HIV-1 ribozyme that produces a 5'- and 3'-trimmed trans-acting ribozyme, targeted against HIV-1 RNA, and cis-acting ribozymes that are designed to bind to and thereby sequester trans-activator proteins such as tat and rev. Nucleic Acids Res 22:5060-5067.
476. Zarrinkar, P.P. and Williamson, J.R. 1994 Kinetic intermediates in RNA folding. Science 265:918-924.
477. Zaug, A.J., Davilaaponte, J.A., and Cech, T.R. 1994 Catalysis of RNA cleavage by a ribozyme derived from the group i intron of anabaena pre-tRNA(Leu). Biochemistry 33:14935-14947.
478. Zimmerly, S., Gamulin, V., Burkard, U., and Söll, D. 1990 The RNA component of RNase P in Schizosaccharomyces species. FEBS Lett. 271:189-193.
479. Zito, K., Huttenhofer, A., and Pace, N.R. 1993 Lead-Catalyzed Cleavage of Ribonuclease P RNA as a Probe for Integrity of Tertiary Structure. Nucleic Acids Res. 21:5916-5920.
480. Zorbas, H., Rogge, L., Meisterernst, M., and Winnacker, E.L. 1989 Hydroxyl radical footprints reveal novel structural features around the NF I binding site in adenovirus DNA. Nucleic Acids Res. 17:7735-7748.
481. Zuker, M., Jaeger, J.A., and Turner, D.H. 1991 A comparison of optimal and suboptimal RNA secondary structures predicted by free energy minimization with structures determined by phylogenetic comparison. Nucleic Acids Res. 19:2707-2714.
482. Zwieb, C., Kim, J., and Adhya, S. 1989 DNA bending by negative regulatory proteins: Gal and Lac repressors. Genes. Dev. 3:606-611.