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Dissertation Information for Daniel Wright

NAME:
- Daniel Wright

DEGREE:
- Ph.D.

DISCIPLINE:
- Library and Information Science

SCHOOL:
- University of Illinois, Urbana-Champaign (USA) (2011)

ADVISORS:
- Les Gasser

COMMITTEE MEMBERS:
- Miles Efron
- Allen Renear
- Zan Luthey-Schulten

MPACT Status: Fully Complete

Title: Information and the evolution of codon bias

Abstract: The informational properties of biological systems are the subject of much debate and research. I present a general argument in favor of the existence and central importance of information in organisms, followed by a case study of the genetic code (specifically, codon bias) and the translation system from the perspective of information. The codon biases of 831 Bacteria and Archeae are analyzed and modeled as points in a 64-dimensional statistical space. The major results are that (1) codon bias evolution does not follow canonical patterns, and (2) the use of coding space in organisms is a subset of the total possible coding space. These findings imply that codon bias is a unique adaptive mechanism that owes its existence to organisms' use of information in representing genes, and that there is a particularly biological character to the resulting biased coding and information use.

MPACT Scores for Daniel Wright

A = 0
C = 0
A+C = 0
T = 0
G = 0
W = 0
TD = 0
TA = 0
calculated 2012-07-30 12:17:28

Advisors and Advisees Graph

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Students under Daniel Wright

ADVISEES:
- None

COMMITTEESHIPS:
- None